Evidence map›Paper›PMID 36440381›Full record

ArticleEFSA journal. European Food Safety Authority2022

Follow-up of the re-evaluation of sulfur dioxide (E 220), sodium sulfite (E 221), sodium bisulfite (E 222), sodium metabisulfite (E 223), potassium metabisulfite (E 224), calcium sulfite (E 226), calcium bisulfite (E 227) and potassium bisulfite (E 228).

EFSA Panel on Food Additives and Flavourings (FAF), Maged Younes, Gabriele Aquilina, Laurence Castle, Karl-Heinz Engel, Paul J Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Ursula Gundert-Remy, Rainer Gürtler and 20 more

Open access · diamondAbstract read
In one paragraph

Article in EFSA journal. European Food Safety Authority, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Storage Stability ofFoods (Basel, Switzerland) · 2025
    Article
  7. Article
  8. Statement on the use and interpretation of the margin of exposure approach.EFSA journal. European Food Safety Authority · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Hypersensitivity Reactions to Food Additives-Preservatives, Antioxidants, Flavor Enhancers.International journal of environmental research and public health · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors.

EFSA Panel on Food Additives and Flavourings (FAF)
Maged Younes
Gabriele Aquilina
Laurence Castle
Karl-Heinz Engel
Paul J Fowler
Maria Jose Frutos Fernandez
Peter Fürst
Ursula Gundert-Remy
Rainer Gürtler
Trine Husøy
Melania Manco
Wim Mennes
Peter Moldeus
Sabina Passamonti
Romina Shah
Ine Waalkens-Berendsen
Polly Boon
Karlien Cheyns
Riccardo Crebelli
Rex FitzGerald
Claude Lambré
Manuela Mirat
Beate Ulbrich
Christiane Vleminckx
Agnieszka Mech
Ana Maria Rincon
Alexandra Tard
Zsuzsanna Horvath
Matthew Wright

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sulfur dioxide-sulfites (E 220-228) were re-evaluated in 2016, resulting in the setting of a temporary ADI of 0.7 mg SO

Indexed as

calcium bisulfitecalcium sulfiteCAS 10257‐55‐3CAS 13780‐03‐5CAS 16731‐55‐8CAS 7446‐09‐5CAS 7631‐90‐5CAS 7681‐57‐4CAS 7757‐83‐7CAS 7773‐03‐7E 220E 221E 222E 223E 224E 226E 227E 228food additivepotassium bisulfitepotassium metabisulfitesodium bisulfitesodium metabisulfitesodium sulfitesulfur dioxide

Identifiers

PMID36440381
PMCPMC9685353
OpenAlexW4309852935

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.