ArticleFrontiers in pediatrics2022
Identifying the research, advocacy, policy and implementation needs for the prevention and management of respiratory syncytial virus lower respiratory tract infection in low- and middle-income countries.
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Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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18citing papers in PubMed, 1 pooled it
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Incidence, hospitalization, and mortality in children aged 5 years and younger with respiratory syncytial virus-related diseases: A systematic review and meta-analysis.Influenza and other respiratory viruses · 2023Pooled it
- Comparison of Sofia 2 Respiratory Syncytial Virus Fluorescent Immunoassay to Real-Time Polymerase Chain Reaction Assay in Children Under Two Years Old Hospitalized With Acute Respiratory Illness in Amman, Jordan: A Cross-Sectional Study.Health science reports · 2025Article
- Respiratory Syncytial Virus Infection in Older Adults in Asia: A Modified Delphi Expert Consensus on Surveillance, Diagnosis, and Prevention.Pulmonary therapy · 2025Article
- Feasibility and Acceptability of Respiratory Syncytial Virus Vaccination in Mothers for Infant Protection at Edward Francis Small Teaching Hospital, the Gambia.Journal of epidemiology and global health · 2025Article
- Proof-of-principle of a technology transfer of a dried blood virus neutralisation assay to a Gavi-eligible country.BMJ global health · 2025Article
- Acute Respiratory Tract Infections in Pediatric Populations of Slum Areas: Navigating Challenges and Dynamics of Immune Responses.Current pediatric reviews · 2025Review
- Time trends in the burden of non-COVID-19 lower respiratory tract infections among children aged 0 to 14 years.Frontiers in cellular and infection microbiology · 2025Article
- Respiratory syncytial virus prophylaxis for children in Africa: Challenges, opportunities and public health strategies.Journal of public health in Africa · 2025Article
- Perceived benefits, information, vaccination history, and conspiracy beliefs as significant determinants of RSV vaccine acceptance among Arab seniors.Therapeutic advances in vaccines and immunotherapy · 2025Article
- Key Challenges to Understanding the Burden of Respiratory Syncytial Virus in Older Adults in Southeast Asia, the Middle East, and North Africa: An Expert Perspective.Advances in therapy · 2024Review
- Understanding the Burden of Respiratory Syncytial Virus in Older Adults in Latin America: An Expert Perspective on Knowledge Gaps.Pulmonary therapy · 2024Review
- Respiratory syncytial virus burden in children under 2 years old in understudied areas worldwide: gap analysis of available evidence, 2012-2022.Frontiers in pediatrics · 2024Review
- The global burden of lower respiratory infections attributable to respiratory syncytial virus in 204 countries and territories, 1990-2019: findings from the Global Burden of Disease Study 2019.Internal and emergency medicine · 2024Article
- The road to approved vaccines for respiratory syncytial virus.NPJ vaccines · 2023Review
- Article
- Evidence, Experience, and Eminence: Building Blocks for Pediatric Pulmonology Practice and Research in India.Indian journal of pediatrics · 2023Article
- Prioritising respiratory syncytial virus prevention in low-income and middle-income countries.The Lancet. Global health · 2023Article
- Estimating the economic burden of respiratory syncytial virus infections in infants in Vietnam: a cohort study.BMC infectious diseases · 2023Article
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Authors and funding
107 authors at 20 institutions in 28 countries.
Xavier Carbonell-EstranyNeonatology Service, Hospital Clinic, Barcelona, Spain.
Eric A F SimõesDepartment of Pediatrics, School of Medicine, University of Colorado, Aurora, CO, United States.
Louis J BontLaboratory of Translational Immunology and Department of Paediatrics, Wilhelmina Children's Hospital, University Medical Centre Utrecht, Utrecht, Netherlands.
Angela GentileEpidemiology Department, Austral University, Buenos Aires, Argentina.
Nusrat HomairaSchool of Women's and Children's Health, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
Marcelo Comerlato ScottaPontificia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.
Renato T SteinPontificia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.
Juan P TorresDepartment of Pediatrics, Division of Pediatric Infectious Diseases, Faculty of Medicine, Universidad de Chile, Santiago, Chile.
Jarju SheikhMedical Research Council Unit The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
Shobha BroorAll India Institute of Medical Sciences, New Delhi, India.
Najwa Khuri-BulosUniversity of Jordan, Amman, Jordan.
D James NokesCentre for Geographic Medicine Research-Coast, Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.
Patrick K MunywokiCentre for Geographic Medicine Research-Coast, Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.
Quique BassatISGlobal, Hospital Clínic - Universitat de Barcelona, Barcelona, Spain.
Arun K SharmaDepartment of Paediatrics, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal.
Sudha BasnetDepartment of Paediatrics, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal.
Maria GarbaAhmadu Bello University/Teaching Hospital, Zaria, Nigeria.
Joanne De Jesus-CornejoResearch Institute for Tropical Medicine, Muntinlupa, Philippines.
Socorro P LupisanRITM-Tohoku Research Collaborating Center for Emerging Infections, Manila, Philippines.
Marta C NunesSouth African Medical Research Council: Vaccines and Infectious Diseases Analytics Research Unit, University of the Witwatersrand, Johannesburg, South Africa.
Maduja DivarathnaDiagnostic and Research Virology Laboratory, Department of Microbiology, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
John R FullartonViolicom Medical Limited, Aldermaston, United Kingdom.
Barry S Rodgers-GrayViolicom Medical Limited, Aldermaston, United Kingdom.
Ian KearyViolicom Medical Limited, Aldermaston, United Kingdom.
Mark Donald C ReñosaResearch Institute for Tropical Medicine, Muntinlupa, Philippines.
Charl VerweyDepartment of Paediatrics and Child Health, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
David P MooreDepartment of Paediatrics and Child Health, Chris Hani Baragwanath Academic Hospital, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Faseeha NoordeenDiagnostic and Research Virology Laboratory, Department of Microbiology, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
Sushil KabraAll India Institute of Medical Sciences, New Delhi, India.
Marynéa Silva do ValeHospital Universitário da Universidade Federal do Maranhão, São Luís, Brazil.
Rolando Paternina-De La OssaHospital Santa Casa de Ribeirão Preto, São Paulo, Brazil.
Cristina MariñoHospital Militar Central, Bogotá, Colombia.
Josep Figueras-AloyNeonatology Service, Hospital Clínic de Barcelona, Barcelona, Spain.
Leonard KrilovNYU Long Island School of Medicine, Mineola, NY, United States.
Eitan BerezinHospital Santa Casa De São Paulo, São Paulo, Brazil.
Heather J ZarChild Health and the SA-MRC Unit on Child and Adolescent Health, Department of Paediatrics, University of Cape Town (UCT), Cape Town, South Africa.
Krishna PaudelMinistry of Health and Population, Kathmandu, Nepal.
Marco Aurelio Palazzi SafadiHospital Santa Casa De São Paulo, São Paulo, Brazil.
Ghassan DbaiboCenter for Infectious Diseases Research, American University of Beirut, Beirut, Lebanon.
Imane JroundiSchool of Medicine and Pharmacy, University Mohamed V, Rabat, Morocco.
Runa JhaNational Public Health Laboratory, Ministry of Health & Population, Teku, Kathmandu, Nepal.
Rukshan A M RafeekDiagnostic and Research Virology Laboratory, Department of Microbiology, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
Rossiclei de Souza PinheiroUniversidade Federal do Amazonas, Manaus, Brazil.
Marianne BrachtCanadian Premature Babies Foundation, Toronto, ON, Canada.
Rohitha MuthugalaNational Hospital - Kandy, Kandy, Sri Lanka.
Marcello LanariIRCCS-Sant'Orsola University Hospital, Bologna, Italy.
Federico Martinón-TorresHospital Clínico Universitario de Santiago, Universidade de Santiago, Santiago, Spain.
Ian MitchellUniversity of Calgary, Calgary, AB, Canada.
Grace IrimuDepartment of Paediatrics and Child Health, University of Nairobi, Nairobi, Kenya.
Apsara PandeyDepartment of Pediatric Nursing, Maharajgunj Nursing Campus, Institute of Medicine, Tribhuwan University, Kathmandu, Nepal.
Anand KrishnanAll India Institute of Medical Sciences, New Delhi, India.
Asuncion MejiasNationwide Childrens Hospital, Columbus, OH, USA.
Marcela Santos Corrêa da CostaHospital Materno-Infantil de Brasília, Brasília, Brazil.
Shrijana ShresthaPatan Academy of Health Sciences, Lalitpur, Nepal.
Jeffrey M PernicaDepartment of Pediatrics, McMaster University, Hamilton, ON, Canada.
Felipe Cotrim de CarvalhoSurveillance Secretariat in Health, Ministry of Health, Brasilia, Brazil.
Rose E JalangoMinistry of Health Kenya, Nairobi, Kenya.
Hafsat IbrahimBayero University/Aminu Kano Teaching Hospital, Kano, Nigeria.
Atana EwaUniversity of Calabar/University of Calabar Teaching Hospital, Calabar, Nigeria.
Gabriela EnsinckHospital de Niños Víctor J. Vilela de Rosario, Santa Fe, Argentina.
Rolando Ulloa-GutierrezHospital Nacional de Niños "Dr. Carlos Sáenz Herrera", Caja Costarricense del Seguro Social (CCSS), San José, Costa Rica.
Alexandre Lopes MiralhaUniversidade Federal do Amazonas, Manaus, Brazil.
Maria Florencia LucionEpidemiology Department, Austral University, Buenos Aires, Argentina.
Md Zakiul HassanInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Zubair AkhtarInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Mohammad Abdul AleemInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Fahmida ChowdhuryInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Pablo RojoUniversity Hospital October 12, Madrid, Spain.
Charles SandeCentre for Geographic Medicine Research-Coast, Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.
Abednego MusauPSI Regional Technical Services Office, Nairobi, Kenya.
Khalequ ZamanInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Luiza HelenaMetropolitan University of Santos, São Paulo, Brazil.
Falleiros ArlantMetropolitan University of Santos, São Paulo, Brazil.
Prakash GhimireDepartment of Paediatrics, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal.
April PriceLondon Health Sciences Centre, London, ON, Canada.
Kalpana Upadhyay SubediParopakar Maternity and Women's Hospital, Kathmandu, Nepal.
Helena Brenes-ChaconHospital Nacional de Niños "Dr. Carlos Sáenz Herrera", Caja Costarricense del Seguro Social (CCSS), San José, Costa Rica.
Doli Rani GoswamiInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Mohammed Ziaur RahmanInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Mohammad Enayet HossainInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Mohammod Jobayer ChistiInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Nestor E VainHospital Sanatorio Trinidad, Buenos Aires, Argentina.
Audrey LimDepartment of Pediatrics, McMaster University, Hamilton, ON, Canada.
Aaron ChiuThe Children's Hospital of Winnipeg, Winnipeg, MB, Canada.
Jesse PapenburgMcGill University, Montreal, QC, Canada.
Maria Del Valle JuarezEpidemiology Department, Austral University, Buenos Aires, Argentina.
Thamarasi SenaratneGeneral Sir John Kotelawala Defence University, Rathmalana, Sri Lanka.
Shiyamalee ArunasalamDiagnostic and Research Virology Laboratory, Department of Microbiology, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.
Tor A StrandUniversity of Bergen, Bergen, Norway.
Adaeze AyukUniversity of Nigeria Teaching Hospital, Enugu, Nigeria.
Olufemi OgunrindeAhmadu Bello University/Teaching Hospital, Zaria, Nigeria.
Lohanna Valeska de Sousa TavaresHospital Infantil Albert Sabin (HIAS), Fortaleza, Ceará, Brazil.
Comfort GarbaAhmadu Bello University/Teaching Hospital, Zaria, Nigeria.
Bilkisu I GarbaUsmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria.
Jeanette DawaWashington State University - Global Health Kenya, Nairobi, Kenya.
Michelle GordonOrillia Soldiers' Memorial Hospital, Orillia, Ontario, Canada.
Eric OsoroWashington State University - Global Health Kenya, Nairobi, Kenya.
Charles N AgotiCentre for Geographic Medicine Research-Coast, Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.
Bryan NyawandaKenya Medical Research Institute- Center for Global Health Research, Centre for Geographic Medicine Research-Coast, Kilifi, Kenya.
Mwanajuma NgamaCentre for Geographic Medicine Research-Coast, Kenya Medical Research Institute-Wellcome Trust Research Programme, Kilifi, Kenya.
Collins TabuMinistry of Health Kenya, Nairobi, Kenya.
Joseph L MathewPost Graduate Institute of Medical Education & Research, Chandigarh, India.
Andrew CornacchiaMinistry of Health Canada, Ottawa, ON, Canada.
Ganesh Kumar RaiNepal Pediatric Society (NEPAS), Kanti Children's Hospital, Kathmandu, Nepal.
Amita JainKing George's Medical University, Uttar Pradesh, India.
Mateus Sfoggia GiongoPontificia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil.
Bosco A PaesDepartment of Pediatrics, McMaster University, Hamilton, ON, Canada.
International Centre for Diarrhoeal Disease Research · BDKenya Medical Research Institute · KEUniversity of Peradeniya · LKAhmadu Bello University Teaching Hospital · NGAll India Institute of Medical Sciences · INAustral University · ARMcMaster University · CAPontifícia Universidade Católica do Rio Grande do Sul · BRSanta Casa Hospital · BRTribhuvan University · NPCosta Rican Department of Social Security · CRHospital Clínic de Barcelona · ESMinistry of Health · KEResearch Institute for Tropical Medicine · PHUniversidade Federal do Amazonas · BRUniversidade Metropolitana de Santos · BRUniversity of the Witwatersrand · ZAWashington State Department of Health · USAmerican University of Beirut · LBBayero University Kano · NG
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The high burden of respiratory syncytial virus (RSV) infection in young children disproportionately occurs in low- and middle-income countries (LMICs). The PROUD (Preventing RespiratOry syncytial virUs in unDerdeveloped countries) Taskforce of 24 RSV worldwide experts assessed key needs for RSV prevention in LMICs, including vaccine and newer preventive measures. Methods: A global, survey-based study was undertaken in 2021. An online questionnaire was developed following three meetings of the Taskforce panellists wherein factors related to RSV infection, its prevention and management were identified using iterative questioning. Each factor was scored, by non-panellists interested in RSV, on a scale of zero (very-low-relevance) to 100 (very-high-relevance) within two scenarios: (1) Current and (2) Future expectations for RSV management. Results: Ninety questionnaires were completed: 70 by respondents (71.4% physicians; 27.1% researchers/scientists) from 16 LMICs and 20 from nine high-income (HI) countries (90.0% physicians; 5.0% researchers/scientists), as a reference group. Within LMICs, RSV awareness was perceived to be low, and management was not prioritised. Of the 100 factors scored, those related to improved diagnosis particularly access to affordable point-of-care diagnostics, disease burden data generation, clinical and general education, prompt access to new interventions, and engagement with policymakers/payers were identified of paramount importance. There was a strong need for clinical education and local data generation in the lowest economies, whereas upper-middle income countries were more closely aligned with HI countries in terms of current RSV service provision. Conclusion: Seven key actions for improving RSV prevention and management in LMICs are proposed.
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burdendecision researchdeveloping countriesdiagnosticsmanagementpreventionRSV
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