Evidence map›Paper›PMID 36440216›Full record

ArticleFrontiers in endocrinology2022

Case report: Two sisters with a germline

Raphaelle D Vallera, Yanli Ding, Kimmo J Hatanpaa, Justin A Bishop, Sasan Mirfakhraee, Abdel A Alli, Sergei G Tevosian, Mouna Tabebi, Oliver Gimm, Peter Söderkvist and 3 more

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Endocrine oncology (Bristol, England) · 2026
    Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Raphaelle D ValleraDepartment of Medicine, Division of Endocrinology, Baylor Scott & White Health, Dallas, TX, United States.
Yanli DingDepartment of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Kimmo J HatanpaaDepartment of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Justin A BishopDepartment of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Sasan MirfakhraeeDepartment of Medicine, Division of Endocrinology, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Abdel A AlliDepartment of Physiology and Functional Genomics, University of Florida, Gainesville, FL, United States.
Sergei G TevosianDepartment of Physiological Sciences, University of Florida, Gainesville, FL, United States.
Mouna TabebiDepartment of Surgery and Department of Biomedical and Clinical Sciences (BKV), Linköping University, Linköping, Sweden.
Oliver GimmDepartment of Surgery and Department of Biomedical and Clinical Sciences (BKV), Linköping University, Linköping, Sweden.
Peter SöderkvistDivision of Cell Biology, Department of Biomedical and Clinical Sciences (BKV), Linköping University, Linköping, Sweden.
Cynthia Estrada-ZunigaDepartment of Medicine, Division of Hematology and Medical Oncology, Mays Cancer Center, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Patricia L M DahiaDepartment of Medicine, Division of Hematology and Medical Oncology, Mays Cancer Center, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Hans K GhayeeDepartment of Medicine, Division of Endocrinology & Metabolism, University of Florida, Malcom Randall VA Medical Center, Gainesville, FL, United States.
The University of Texas Health Science Center at San Antonio · USThe University of Texas Southwestern Medical Center · USUniversity of Florida · USLinköping University · SEBaylor Scott & White Health · USScience for Life Laboratory · SE

Funding

Institute for Integration of Medicine & Science: A Partnership to Improve HealthUL1TR002645 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, HARGREAVES, KENNETH M · 2018 to 2022
$20.4M
Institute for Integration of Medicine & Science: A Partnership to Improve HealthUL1TR001120 · NCATS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CLARK, ROBERT A, HARGREAVES, KENNETH M · 2013 to 2017
$16.5M
Interaction of the TMEM127 tumor suppressor with the mTORC1 lysosomal activating complexR01GM114102 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI DAHIA, PATRICIA LEAL · 2017 to 2021
$1.5M
NCATS NIH HHS UL1 TR001120NCATS NIH HHS UL1 TR002645NIGMS NIH HHS R01 GM114102
6 · The paper itself

Abstract

Genetic testing has become the standard of care for many disease states. As a result, physicians treating patients who have tumors often rely on germline genetic testing results for making clinical decisions. Cases of two sisters carrying a germline

Indexed as

Adrenal Gland NeoplasmsPheochromocytomaPituitary NeoplasmsCheckpoint Kinase 2FemaleHumansSiblingsCheckpoint Kinase 2CHEK2 protein, humanCHEK2germlineNF1PCCPNETsomatictumor

Identifiers

PMID36440216
PMCPMC9682564
OpenAlexW4308448006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.