Evidence map›Paper›PMID 36440187›Full record

ReviewFrontiers in endocrinology2022

The use of temozolomide in paediatric metastatic phaeochromocytoma/paraganglioma: A case report and literature review.

Calum Urquhart, Ben Fleming, Ines Harper, Luigi Aloj, Ruth Armstrong, Liz Hook, Anna-May Long, Claire Jackson, Ferdia A Gallagher, Mary A McLean and 5 more

Open access · goldAbstract readReviewCase Reports
In one paragraph

Review in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Calum UrquhartDepartment of Diabetes and Endocrinology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Ben FlemingDepartment of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Ines HarperDepartment of Nuclear Medicine, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Luigi AlojDepartment of Nuclear Medicine, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Ruth ArmstrongDepartment of Clinical Genetics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Liz HookDepartment of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Anna-May LongDepartment of Paediatric Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Claire JacksonDepartment of Paediatric Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Ferdia A GallagherDepartment of Radiology, University of Cambridge, Cambridge, United Kingdom.
Mary A McLeanDepartment of Radiology, University of Cambridge, Cambridge, United Kingdom.
Patrick TarpeyDepartment of Clinical Genetics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Vasilis KosmoliaptsisDepartment of Surgery and NIHR Biomedical Research Centre, University of Cambridge and Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
James NicholsonDepartment of Paediatric Oncology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
A Emile J HendriksDepartment of Paediatrics, University of Cambridge, Cambridge, United Kingdom.
Ruth T CaseyDepartment of Diabetes and Endocrinology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Cambridge University Hospitals NHS Foundation Trust · GBUniversity of Cambridge · GB

Funding

Cancer Research UK 16628Cancer Research UK 27150Cancer Research UK 28667
6 · The paper itself

Abstract

There is increasing evidence to support the use of temozolomide therapy for the treatment of metastatic phaeochromocytoma/paraganglioma (PPGL) in adults, particularly in patients with

Indexed as

Adrenal Gland NeoplasmsBrain NeoplasmsNeoplasms, Second PrimaryParagangliomaPheochromocytomaAdultChildFemaleHumansPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadionuclide ImagingTemozolomidecopper dotatate CU-64TemozolomideparagangliomapheochromocytomaSDHB = SDH enzyme complex subunit Bsuccinate dehydrogenase (SDH)temozolomide

Identifiers

PMID36440187
PMCPMC9681996
OpenAlexW4308726170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.