Evidence map›Paper›PMID 36440032›Full record

ArticleFrontiers in cardiovascular medicine2022

Association between remnant cholesterol and arterial stiffness in a Chinese community-based population: A cross-sectional study.

Jiahui Liu, Fangfang Fan, Bo Liu, Kaiyin Li, Yimeng Jiang, Jia Jia, Chuyun Chen, Bo Zheng, Yan Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. The Impact of the Blood Lipids Levels on Arterial Stiffness.Journal of cardiovascular development and disease · 2023
    Review
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jiahui LiuDepartment of Cardiology, Institute of Cardiovascular Disease, Peking University First Hospital, Beijing, China.
Fangfang FanDepartment of Cardiology, Institute of Cardiovascular Disease, Peking University First Hospital, Beijing, China.
Bo LiuDepartment of Cardiology, Institute of Cardiovascular Disease, Peking University First Hospital, Beijing, China.
Kaiyin LiDepartment of Cardiology, Institute of Cardiovascular Disease, Peking University First Hospital, Beijing, China.
Yimeng JiangDepartment of Cardiology, Institute of Cardiovascular Disease, Peking University First Hospital, Beijing, China.
Jia JiaDepartment of Cardiology, Institute of Cardiovascular Disease, Peking University First Hospital, Beijing, China.
Chuyun ChenDepartment of Cardiology, Institute of Cardiovascular Disease, Peking University First Hospital, Beijing, China.
Bo ZhengDepartment of Cardiology, Institute of Cardiovascular Disease, Peking University First Hospital, Beijing, China.
Yan ZhangDepartment of Cardiology, Institute of Cardiovascular Disease, Peking University First Hospital, Beijing, China.
Peking University First Hospital · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: As a surrogate of arterial stiffness, the brachial-ankle pulse wave velocity (baPWV) is a good predictor of incident cardiovascular disease. Remnant cholesterol (RC) is a proven independent risk factor for cardiovascular disease. However, the relationship between RC and baPWV is unknown. The present study was performed to explore this relationship. Design: Cross-sectional study. Setting and participants: This study involved 8,028 participants of a community-based atherosclerosis cohort from China. Community residents aged ≥40 years were enrolled by responding to detailed research recruitment posters or by phone invitation. The participants comprised 2,938 (36.60%) men, and their mean age was 56.57 ± 9.04 years. Methods and results: The baPWV was measured with a standard protocol using the Omron Colin BP-203RPE III device (Omron Healthcare, Kyoto, Japan). RC was calculated as follows: RC = TC - LDL-C - HDL-C. The mean baPWV was 1,646.85 ± 374.11 cm/s. The median RC concentration was 0.56 (0.41-0.74) mmol/L. In the multivariate logistic regression analyses, the concentrations of RC, triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and non-high-density lipoprotein cholesterol (non-HDL-C) were all positively and independently associated with baPWV. The baPWV was higher in the fourth than first lipid profile quartile. The HDL-C concentration was inversely associated with baPWV. When RC was forced into the model with other lipid profile indices simultaneously, only the RC and TG concentrations remained significantly associated with baPWV. Conclusion: Lipids are independently associated with baPWV. The RC and TG concentrations have stronger associations with arterial stiffness than other lipid indices in the Chinese community-based population.

Indexed as

arterial stiffnessbrachial-ankle pulse wave velocitycross-sectional studylipidsremnant cholesterol

Identifiers

PMID36440032
PMCPMC9691684
OpenAlexW4308937897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.