Evidence map›Paper›PMID 36440025›Full record

ReviewFrontiers in cardiovascular medicine2022

Epigenetic regulation in myocardial infarction: Non-coding RNAs and exosomal non-coding RNAs.

Sara Fadaei, Fatemeh Zarepour, Mehrnoosh Parvaresh, Alireza Motamedzadeh, Seyed Saeed Tamehri Zadeh, Amirhossein Sheida, Mohammad Shabani, Michael R Hamblin, Mehdi Rezaee, Maryam Zarei and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

  1. Empagliflozin modulates microRNA expression in human primary cardiomyocytes under CoClInternational journal of cardiology. Cardiovascular risk and prevention · 2026
    Article
  2. Review
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  8. Feasibility study of core training in knee injury recovery.Turkish journal of physical medicine and rehabilitation · 2025
    Article
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. New Insights into the Reparative Angiogenesis after Myocardial Infarction.International journal of molecular sciences · 2023
    Review
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Sara FadaeiDepartment of Internal Medicine and Endocrinology, Shohadae Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Fatemeh ZarepourStudent Research Committee, Kashan University of Medical Sciences, Kashan, Iran.
Mehrnoosh ParvareshDepartment of Physical Medicine and Rehabilitation, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran.
Alireza MotamedzadehDepartment of Internal Medicine, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
Seyed Saeed Tamehri ZadehSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Amirhossein SheidaStudent Research Committee, Kashan University of Medical Sciences, Kashan, Iran.
Mohammad ShabaniStudent Research Committee, Kashan University of Medical Sciences, Kashan, Iran.
Michael R HamblinLaser Research Centre, Faculty of Health Science, University of Johannesburg, Doornfontein, South Africa.
Mehdi RezaeeDepartment of Anesthesiology, School of Medicine, Shahid Madani Hospital, Alborz University of Medical Sciences, Karaj, Iran.
Maryam ZareiTehran Heart Center, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
Hamed MirzaeiResearch Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran.
Kashan University of Medical Sciences · IRTehran University of Medical Sciences · IRAlborz University of Medical SciencesShahid Beheshti University of Medical Sciences · IRUniversity of Isfahan · IRUniversity of Johannesburg · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction (MI) is one of the leading causes of deaths globally. The early diagnosis of MI lowers the rate of subsequent complications and maximizes the benefits of cardiovascular interventions. Many efforts have been made to explore new therapeutic targets for MI, and the therapeutic potential of non-coding RNAs (ncRNAs) is one good example. NcRNAs are a group of RNAs with many different subgroups, but they are not translated into proteins. MicroRNAs (miRNAs) are the most studied type of ncRNAs, and have been found to regulate several pathological processes in MI, including cardiomyocyte inflammation, apoptosis, angiogenesis, and fibrosis. These processes can also be modulated by circular RNAs and long ncRNAs

Indexed as

circular RNAsexosomelong non-coding RNAsmicroRNAsmyocardial infarctionnon-coding RNAs

Identifiers

PMID36440025
PMCPMC9685618
OpenAlexW4308875865

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.