SynthesisFrontiers in cardiovascular medicine2022
Microcirculation function assessment in acute myocardial infarction: A systematic review of microcirculatory resistance indices.
Synthesis in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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Who cites it
14 citing papers in PubMed, 15 citations in OpenAlex.
- A single-center observational study on the impact of intravascular ultrasound-detected attenuated plaque on coronary microvascular dysfunction following percutaneous coronary intervention.The international journal of cardiovascular imaging · 2026Observational
- Stress hyperglycemia ratio is associated with microcirculatory resistance in patients with ST-segment elevation myocardial infarction.BMC cardiovascular disorders · 2026Observational
- Insulin or Dapagliflozin Potentially Improves Microcirculatory Dysfunction or INOCA Related to Culprit Vessels in Diabetic Patients With STEMI After DCB Therapy During Long-Term Follow-Up.Journal of diabetes · 2026Observational
- Arterial Supply to the Atrioventricular Node: Anatomical Variability and Clinical Implications.Arrhythmia & electrophysiology review · 2026Review
- c-FLIP Protects Cardiac Microcirculation in Sepsis-Induced Myocardial Dysfunction Via FUNDC1-Mediated Regulation of Mitochondrial Autophagy.JACC. Basic to translational science · 2025Article
- Construction and Clinical Relevance of a Predictive Model of Coronary Microcirculatory Dysfunction in Patients With Acute Myocardial Infarction Following Percutaneous Coronary Intervention.Reviews in cardiovascular medicine · 2025Article
- Microcirculation Function in Non-ST-Elevation Myocardial Infarction After the Index Event and at Follow-Up Assessment.CJC open · 2025Article
- Epicardial fat volume assessment and strain analysis by cardiac magnetic resonance: a novel method for evaluating microcirculation dysfunction after myocardial infarction.Cardiovascular diagnosis and therapy · 2025Article
- Triglyceride-glucose index is associated with microcirculatory resistance in patients with type 2 diabetes and STEMI undergoing primary PCI.Scientific reports · 2025Article
- Cardiac T1 mapping in non-ST-segment elevation myocardial infarction: temporal changes in myocardial fibrosis.Frontiers in cardiovascular medicine · 2025Article
- Relationship Between Cardiometabolic Index and Post-PCI Coronary Microvascular Dysfunction in Acute STEMI Patients.Journal of multidisciplinary healthcare · 2025Article
- Peripheral microvessel area better predicts the severity of coronary stenosis of acute myocardial infarction patients over pulse wave velocity.Scientific reports · 2024Article
- Review
- Coronary Microcirculation: The Next Frontier in the Management of STEMI.Journal of clinical medicine · 2023Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Up to 50% of acute myocardial infarction (MI) patients present with microvascular dysfunction, after a successful percutaneous coronary intervention (PCI), which leads to worse clinical outcomes. The main purpose of this study is to provide a critical appraisal of the emerging role of invasive microvascular resistance indices in the MI setting, using the index of microcirculatory resistance (IMR), hyperemic microvascular resistance (HMR) and zero-flow pressure (Pzf). Methods: We systematically explored relevant studies in the context of MI that correlated microcirculation resistance indices with microvascular dysfunction on cardiac magnetic resonance (CMR), microvascular dysfunction occurring in infarct related arteries (IRA) and non-IRA and its relation to clinical outcomes. Results: The microcirculation resistance indices correlated significantly with microvascular obstruction (MVO) and infarct size (IS) on CMR. Although HMR and Pzf seem to have better diagnostic accuracy for MVO and IS, IMR has more validation data. Although, both IMR and HMR were independent predictors of adverse cardiovascular events, HMR has no validated cut-off value and data is limited to small observational studies. The presence of microvascular dysfunction in non-IRA does not impact prognosis. Conclusion: Microvascular resistance indices are valuable means to evaluate microcirculation function following MI. Microvascular dysfunction relates to the extent of myocardial damage and clinical outcomes after MI. Systematic review registration: [https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021228432], identifier [CRD42021228432].
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.