Evidence map›Paper›PMID 36439971›Full record

ReviewIBRO neuroscience reports2022

MicroRNAs as a possible biomarker in the treatment of multiple sclerosis.

Moisés Manuel Gallardo Pérez, Solón Javier Garcés Eisele

Abstract readReview
In one paragraph

Review in IBRO neuroscience reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Is Obesity a Modifiable Risk Factor in Multiple Sclerosis? Mechanistic Insights into Neuroinflammation and Oxidative Damage.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Moisés Manuel Gallardo PérezUniversidad Popular Autónoma del Estado de Puebla, Puebla, Mexico.
Solón Javier Garcés EiseleUniversidad Popular Autónoma del Estado de Puebla, Puebla, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis (MS) is a demyelinating, autoimmune and inflammatory disease that affects the central nervous system (CNS) and is one of the leading causes of disability in young adults worldwide. There are different drugs for the treatment of MS that aim to modify the natural course of the disease and thus slow its progression. This group of drugs is known as disease modifying therapy (DMT). To evaluate the effectiveness of these drugs, mainly clinical and MRI parameters are used. In recent years, different studies have emerged that propose the use of biomarkers to improve the evaluation of the effectiveness of DMT and to provide individualized therapy. MicroRNAs (miRNAs) are part of these biomarkers that have been proposed both for their wide availability in different tissues and body fluids and for their possible involvement in different biological processes. In this review we briefly discuss the mechanisms of action of drugs available for the treatment of MS, as well as recent findings on the expression levels of different miRNAs in MS patients under treatment with DMT.

Indexed as

BiomarkerDisease modifying therapyMicroRNAMultiple sclerosis

Identifiers

PMID36439971
PMCPMC9685387

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.