Evidence map›Paper›PMID 36439947›Full record

ArticleJournal of inflammation research2022

Resolved Hypereosinophilic Syndrome and Immune Thrombocytopenic Purpura in Ulcerative Colitis Patients Post Colectomy: A Case Series and Literature Review.

Ahmed Hussein Subki, Manal Ismail Bokhary, Sultan Abdulrahman Alandijani, Mohannad Abdulrahman Aljehani, Ahmed Wasel Alharbi, May Alzahrani, Saud Suliman Almuhammadi, Bassim Tahseen Albeirouti, Mohamed Abdulmajid Abduljabar, Silvio Danese

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of inflammation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Ahmed Hussein SubkiDepartment of Internal Medicine, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia.ORCID 0000-0002-0430-0321
Manal Ismail BokharyDepartment of Internal Medicine, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia.
Sultan Abdulrahman AlandijaniDepartment of Internal Medicine, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia.
Mohannad Abdulrahman AljehaniDepartment of Internal Medicine, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia.
Ahmed Wasel AlharbiDepartment of Internal Medicine, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia.
May AlzahraniDepartment of Internal Medicine, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia.
Saud Suliman AlmuhammadiDepartment of Surgery, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia.
Bassim Tahseen AlbeiroutiAdult Hematology/Bone Marrow Transplant (BMT) Section, Department of Oncology, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia.
Mohamed Abdulmajid AbduljabarDepartment of Internal Medicine, King Faisal Specialist Hospital & Research Centre, Jeddah, Saudi Arabia.
Silvio DaneseGastroenterology and Endoscopy, IRCCS San Raffaele Hospital and Vita-Salute San Raffaele University, Milan, Italy.
King Faisal Specialist Hospital & Research Centre · SAVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Hypereosinophilic syndrome (HES) and immune thrombocytopenic purpura (ITP) have been reported to co-occur with ulcerative colitis (UC). However, the exact pathogenic mechanisms of their occurrence remain elusive. In this article, we aim to describe two cases of UC patients who developed refractory HES and ITP and elaborate on their potential pathogenesis. Case Study: We report two middle-aged patients diagnosed with UC. The first patient developed HES that was refractory to conventional medical therapy of idiopathic HES, and the second developed refractory ITP that failed steroid and immunosuppressive therapy. Both conditions improved considerably following colectomy, suggesting they are of a reactive rather than idiopathic nature. Conclusion: In patients with UC and refractory comorbid HES or ITP, the reactive nature of these comorbidities should be taken into consideration, and colectomy, therefore, should be considered if clinically indicated.

Indexed as

colectomyhypereosinophilic syndromeimmune thrombocytopenic purpuraulcerative colitis

Identifiers

PMID36439947
PMCPMC9697402
OpenAlexW4309749315

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.