Evidence map›Paper›PMID 36439831›Full record

ArticleFrontiers in microbiology2022

Directed evolution engineering to improve activity of glucose dehydrogenase by increasing pocket hydrophobicity.

Li Hua, Bao Qianqian, Zhao Jianfeng, Xu Yinbiao, Yang Shengyu, Xue Weishi, Sun Yang, Liu Yupeng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. A Unique Insertion Loop Facilitates Tight NADInternational journal of molecular sciences · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Li HuaSchool of Life Sciences, Institute of Microbial Engineering, Henan University, Kaifeng, China.
Bao QianqianSchool of Life Sciences, Institute of Microbial Engineering, Henan University, Kaifeng, China.
Zhao JianfengSchool of Life Sciences, Institute of Microbial Engineering, Henan University, Kaifeng, China.
Xu YinbiaoSchool of Life Sciences, Institute of Microbial Engineering, Henan University, Kaifeng, China.
Yang ShengyuSchool of Life Sciences, Institute of Microbial Engineering, Henan University, Kaifeng, China.
Xue WeishiSchool of Life Sciences, Institute of Microbial Engineering, Henan University, Kaifeng, China.
Sun YangSchool of Life Sciences, Institute of Microbial Engineering, Henan University, Kaifeng, China.
Liu YupengSchool of Life Sciences, Institute of Microbial Engineering, Henan University, Kaifeng, China.
Henan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glucose dehydrogenase (GDH) is a NAD(P)

Indexed as

AlphaFold2glucose dehydrogenasehydrophobicityorganic solventssite-directed mutagenesis

Identifiers

PMID36439831
PMCPMC9681798
OpenAlexW4308723878

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.