Evidence map›Paper›PMID 36439767›Full record

ArticleHeliyon2022

Longitudinal antibody titer, avidity, and neutralizing responses after SARS-CoV-2 infection.

Jonathon M Monroe, Iana H Haralambieva, Nathaniel D Warner, Diane E Grill, Huy Quang Quach, Richard B Kennedy

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jonathon M MonroeMayo Clinic Vaccine Research Group, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Iana H HaralambievaMayo Clinic Vaccine Research Group, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Nathaniel D WarnerDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
Diane E GrillDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA.
Huy Quang QuachMayo Clinic Vaccine Research Group, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Richard B KennedyMayo Clinic Vaccine Research Group, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic in Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While waning immunity and SARS-CoV-2 variant immune escape continue to result in high infection rates worldwide, associations between longitudinal quantitative, qualitative, and functional humoral immune responses after SARS-CoV-2 infection remain unclear. In this study, we found significant waning of antibody against Spike S1 (R = -0.32, p = 0.035) and N protein (R = -0.39, p = 0.008), while RBD antibody moderately decreased (R = -0.19, p = 0.203). Likewise, neutralizing antibody titer (ND

Indexed as

Antibody avidityCOVID-19Humoral immunityLongitudinal immunityNeutralizationSARS-CoV-2

Identifiers

PMID36439767
PMCPMC9675084
OpenAlexW4309569769

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.