Evidence map›Paper›PMID 36439558›Full record

ReviewCureus2022

Haloperidol Versus Atypical Antipsychotics for Treating Delirium in Intensive Care Unit Patients: A Systematic Review.

Akhil Sadhu, Carla Valencia, Hameeda Fatima, Ijeoma Nwankwo, Mahvish Anam, Shrinkhala Maharjan, Zainab Amjad, Abdelrahman Abaza, Advait M Vasavada, Safeera Khan

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 4 countries.

Akhil SadhuFamily Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Carla ValenciaInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Hameeda FatimaResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Ijeoma NwankwoResearch, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Mahvish AnamInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Shrinkhala MaharjanInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Zainab AmjadInternal Medicine, King Faisal University, Al-Ahsa, SAU.
Abdelrahman AbazaPathology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Advait M VasavadaInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Safeera KhanInternal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
M. P. Shah Medical College · INCalifornia Institute of Behavioral Neurosciences and Psychology (United States) · USKing Faisal University · SACivil Hospital Karachi · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delirium is a severe and variable neuropsychiatric illness that causes cognitive and behavioral problems as well as abrupt impairment in consciousness and focus. Due to the complex, dynamic, and multifaceted interactions between several risk factors, the etiology of delirium is unclear. Although its efficacy has not been thoroughly studied, haloperidol, a common antipsychotic medicine, is frequently used to prevent delirium in critically ill patients. When evaluating the atypical antipsychotic response rates for treating delirium, only a few trials have taken age into account.  Articles were searched for from PubMed, PubMed Central (PMC), and Science Direct, and reviewed systematically. A complete 225 articles were identified after applying the search strategy to these databases. Out of these, 12 were finalized for review. We reviewed the efficacy and safety of haloperidol with atypical antipsychotics for treating delirium in intensive care unit patients.

Indexed as

atypicalantipsychoticsdeliriumhaloperidolintensive care unit staypharmacology

Identifiers

PMID36439558
PMCPMC9683743
OpenAlexW4307173327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.