SynthesisFrontiers in oncology2022
Mapping global epidemiology of thyroid nodules among general population: A systematic review and meta-analysis.
Synthesis in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
78 citing papers in PubMed, 8 syntheses or guidelines pooled it, 101 citations in OpenAlex.
- ESR Essentials: thyroid imaging-practice recommendations by the European Society of Head and Neck Radiology.European radiology · 2026Guideline
- Ablative Technologies for Thyroid Nodules: A Health Technology Assessment.Ontario health technology assessment series · 2026Pooled it
- The myth of iodine: A systematic review and meta-analysis on the relationship between iodine and thyroid nodule.Journal of endocrinological investigation · 2025Pooled it
- Pooled it
- Pooled it
- Diagnostic performance of ultrasound characteristics-based artificial intelligence models for thyroid nodules: a systematic review and meta-analysis.Frontiers in oncology · 2025Pooled it
- Raman Spectroscopy as a Potential Adjunct of Thyroid Nodule Evaluation: A Systematic Review.International journal of molecular sciences · 2023Pooled it
- Prevalence of clinical signs, symptoms and comorbidities at diagnosis of acromegaly: a systematic review in accordance with PRISMA guidelines.Pituitary · 2023Pooled it
- Severe neck pain: a report of 3 cases of spontaneous thyroid nodule hemorrhage.JCEM case reports · 2026Article
- Diagnostic accuracy of ultrasound, computed tomography, and magnetic resonance imaging for the evaluation of thyroid nodules.The Cochrane database of systematic reviews · 2026Article
- Article
- Thyroid abnormalities in acromegaly in the era of improved disease control: a two-stage study.Journal of endocrinological investigation · 2026Article
- National Trends in Thyroidectomy and Molecular Diagnostic Utilization: A Medicare Analysis (2016-2023).The Laryngoscope · 2026Article
- Multimodal Ultrasound-Based Decision Support for Bethesda IV Thyroid Nodules: Integration of Clinical, Radiomics, Deep Learning, and Topological Features.Journal of imaging informatics in medicine · 2026Article
- Diagnostic Accuracy of Combined Fine-Needle Aspiration Biopsy and Ultrasonography for Malignancy in Bethesda III-IV Thyroid Nodules.Journal of clinical medicine · 2026Article
- Predicting malignancy in solid thyroid nodules with no or punctate-linear enhancement on contrast-enhanced ultrasound: a retrospective analysis.Quantitative imaging in medicine and surgery · 2026Article
- Precision medicine in thyroid nodules: current strategies, challenges, and future directions.Hormones (Athens, Greece) · 2026Review
- Evaluation of large language models for TI-RADS category extraction from free-text thyroid US reports: a comparative study with human readers.Endocrine · 2026Article
- Marine-Lenhart syndrome: why nuclear medicine imaging remains essential for diagnosis and treatment.European journal of nuclear medicine and molecular imaging · 2026Review
- Pentraxin-3 in thyroid nodules: a systemic marker of pathology and a local mediator of inflammation and carcinoma.Frontiers in endocrinology · 2026Article
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: An emerging public health issue is brought on by the worldwide increase of thyroid nodules (TNs). The goal of the current study is to determine the global prevalence of TNs among the general population. Methods: We screened articles published from January 2000 to May 2022. TN prevalence was calculated with the DerSimonian-Laird random effects model with arcsine transformation. Results: A total of 20,358 entries were found in our research, and 102 of them met our inclusion criteria. A total of 9,276,178 individuals have been diagnosed as TNs; the overall prevalence was 24.83% (95% CI 21.44-28.55), regardless of the diagnostic techniques. TNs have become more prevalent during 2012-2022 (29.29%) compared with 2000-2011 (21.53%, Discussion: This meta-analysis shows that, regardless of country development and economic status, TNs are spreading more widely over the world. Our findings showed a strong correlation between rising TN prevalence and older age, female sex, and elevated weight. To stop the TN epidemic from spreading over the world, increased awareness, the understanding of the disease, and quick action are required.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.