Evidence map›Paper›PMID 36439222›Full record

ArticleFrontiers in cellular and infection microbiology2022

A prospective multicenter study on varicella-zoster virus infection in children with acute lymphoblastic leukemia.

Peifang Xiao, Jiaoyang Cai, Ju Gao, Wei Gao, Xianmin Guan, Alex Wing Kwan Leung, Yiying He, Yong Zhuang, Jinhua Chu, Xiaowen Zhai and 14 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 20 institutions in 1 country.

Peifang XiaoDepartment of Hematology, Jiangsu Children Hematology and Oncology Center Children's Hospital of Soochow University, Suzhou, China.
Jiaoyang CaiDepartment of Hematology/Oncology, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, National Health Committee Key Laboratory of Pediatric Hematology and Oncology, Shanghai, China.
Ju GaoDepartment of Pediatrics, West China Second University Hospital, Sichuan University, Key Laboratory of Birth Defects and Related Disease of Women and Children, Ministry of Education, Chengdu, China.
Wei GaoDepartment of Hematology, Jiangsu Children Hematology and Oncology Center Children's Hospital of Soochow University, Suzhou, China.
Xianmin GuanDepartment of Hematology/Oncology, Chongqing Medical University Affiliated Children's Hospital, Chongqing, China.
Alex Wing Kwan LeungDepartment of Pediatrics, Hong Kong Children's Hospital, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Yiying HeDepartment of Hematology/Oncology, Guangzhou Women and Children's Medical Center, Guangzhou, China.
Yong ZhuangDepartment of Pediatrics, Qilu Hospital of Shandong University, Jinan, China.
Jinhua ChuDepartment of Pediatrics, Anhui Medical University Second Affiliated Hospital, Anhui, China.
Xiaowen ZhaiDepartment of Hematology/Oncology, Children's Hospital of Fudan University, Shanghai, China.
Benquan QiDepartment of Pediatrics, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
Aiguo LiuDepartment of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Liangchun YangDepartment of Pediatrics, Xiangya Hospital Central South University, Changsha, China.
Jiashi ZhuDepartment of Hematology/Oncology, Children's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai, China.
Zheng LiDepartment of Hematology/Oncology, Jiangxi Provincial Children's Hospital, Nanchang, China.
Xin TianDepartment of Hematology/Oncology, KunMing Children's Hospital, Kunming, China.
Yao XueDepartment of Hematology/Oncology, Children's Hospital of Nanjing Medical University, Nanjing, China.
Li HaoDepartment of Hematology/Oncology, Xi'an Northwest Women's and Children's Hospital, Xi'an, China.
Xuedong WuDepartment of Pediatrics, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Fen ZhouDepartment of Pediatrics, Xiehe Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Lingzhen WangDepartment of Pediatrics, The Affiliated Hospital of Qingdao Medical University, Qingdao, China.
Jingyan TangDepartment of Hematology/Oncology, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, National Health Committee Key Laboratory of Pediatric Hematology and Oncology, Shanghai, China.
Shuhong ShenDepartment of Hematology/Oncology, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, National Health Committee Key Laboratory of Pediatric Hematology and Oncology, Shanghai, China.
Shaoyan HuDepartment of Hematology, Jiangsu Children Hematology and Oncology Center Children's Hospital of Soochow University, Suzhou, China.
Soochow University · CNShanghai Jiao Tong University · CNAffiliated Hospital of Qingdao University · CNAnhui Medical University · CNCentral South University · CNChildren's Hospital of Fudan University · CNChinese University of Hong Kong · CNChongqing Medical University · CNGuangzhou Medical University · CNHuazhong University of Science and Technology · CNInstitute of Hematology & Blood Diseases Hospital · CNJiangxi Provincial Children's Hospital · CNKunming Children's Hospital · CNNorthwest Women's and Children's Hospital · CNQilu Hospital of Shandong University · CNSecond Affiliated Hospital of Nanjing Medical University · CNShanghai Children's Hospital · CNShanghai Children's Medical Center · CNSichuan University · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and methods: The study evaluated prognostic factors associated with varicella-zoster virus (VZV) infection and mortality in children with acute lymphoblastic leukemia (ALL) using data from the multicenter Chinese Children's Cancer Group ALL-2015 trial. Results: In total, 7,640 patients were recruited, and 138 cases of VZV infection were identified. The incidence of VZV infection was higher in patients aged ≥ 10 years (22.5%) and in patients with the Conclusion: VZV exposure was associated with an increased incidence of complex VZV infection and contributed to VZV-associated death in children with ALL.

Indexed as

ChickenpoxPrecursor Cell Lymphoblastic Leukemia-LymphomaChildHerpesvirus 3, HumanHumansIncidenceProspective Studiesacute lymphoblastic leukemiachildhoodE2A/PBX1 fusion generisk factorvaricella-zoster infection

Identifiers

PMID36439222
PMCPMC9691833
OpenAlexW4308936099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.