Evidence map›Paper›PMID 36439195›Full record

ArticleFrontiers in neuroanatomy2022

HOA2.0-ComPaRe: A next generation Harvard-Oxford Atlas comparative parcellation reasoning method for human and macaque individual brain parcellation and atlases of the cerebral cortex.

Richard Jarrett Rushmore, Sylvain Bouix, Marek Kubicki, Yogesh Rathi, Edward Yeterian, Nikos Makris

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroanatomy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

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  6. Effects of Lateralization of Language on Cognition Among Left-Handers.Neurobiology of language (Cambridge, Mass.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Richard Jarrett RushmoreDepartment of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, United States.
Sylvain BouixPsychiatry Neuroimaging Laboratory, Brigham and Women's Hospital, Boston, MA, United States.
Marek KubickiPsychiatry Neuroimaging Laboratory, Brigham and Women's Hospital, Boston, MA, United States.
Yogesh RathiPsychiatry Neuroimaging Laboratory, Brigham and Women's Hospital, Boston, MA, United States.
Edward YeterianCenter for Morphometric Analysis, Massachusetts General Hospital, Boston, MA, United States.
Nikos MakrisDepartment of Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, United States.
Brigham and Women's Hospital · USMassachusetts General Hospital · USBoston University · USColby College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Comparative structural neuroanatomy is a cornerstone for understanding human brain structure and function. A parcellation framework that relates systematically to fundamental principles of histological organization is an essential step in generating structural comparisons between species. In the present investigation, we developed a comparative parcellation reasoning system (ComPaRe), which is a formal ontological system in human and non-human primate brains based on the cortical cytoarchitectonic mapping used for both species as detailed by Brodmann. ComPaRe provides a theoretical foundation for mapping neural systems in humans and other species using neuroimaging. Based on this approach, we revised the methodology of the original Harvard-Oxford Atlas (HOA) system of brain parcellation to produce a comparative framework for the human (hHOA) and the rhesus monkey (mHOA) brains, which we refer to as HOA2.0-ComPaRe. In addition, we used dedicated segmentation software in the publicly available 3D Slicer platform to parcellate an individual human and rhesus monkey brain. This method produces quantitative morphometric parcellations in the individual brains. Based on these parcellations we created a representative template and 3D brain atlas for the two species, each based on a single subject. Thus, HOA2.0-ComPaRe provides a theoretical foundation for mapping neural systems in humans and other species using neuroimaging, while also representing a significant revision of the original human and macaque monkey HOA parcellation schemas. The methodology and atlases presented here can be used in basic and clinical neuroimaging for morphometric (volumetric) analysis, further generation of atlases, as well as localization of function and structural lesions.

Indexed as

atlascerebral cortexcortical parcellationHarvard-Oxford AtlasmacaqueMRI

Identifiers

PMID36439195
PMCPMC9684647
OpenAlexW4308871322

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.