Evidence map›Paper›PMID 36439097›Full record

ReviewFrontiers in immunology2022

Artificial intelligence for precision medicine in autoimmune liver disease.

Alessio Gerussi, Miki Scaravaglio, Laura Cristoferi, Damiano Verda, Chiara Milani, Elisabetta De Bernardi, Davide Ippolito, Rosanna Asselta, Pietro Invernizzi, Jakob Nikolas Kather and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Radiomics-Based Prognostication in Primary Sclerosing Cholangitis: A Proof-of-Concept Study.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Article
  8. Review
  9. Review
  10. Review
  11. Risk Stratification in Primary Biliary Cholangitis.Journal of clinical medicine · 2023
    Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Alessio GerussiDivision of Gastroenterology, Center for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Miki ScaravaglioDivision of Gastroenterology, Center for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Laura CristoferiDivision of Gastroenterology, Center for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Damiano VerdaRulex Inc., Newton, MA, United States.
Chiara MilaniDivision of Gastroenterology, Center for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Elisabetta De BernardiDepartment of Medicine and Surgery and Tecnomed Foundation, University of Milano - Bicocca, Monza, Italy.
Davide IppolitoDepartment of Radiology, San Gerardo Hospital, Monza, Italy.
Rosanna AsseltaHumanitas Clinical and Research Center, Rozzano, Milan, Italy.
Pietro InvernizziDivision of Gastroenterology, Center for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Jakob Nikolas KatherDepartment of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.
Marco CarboneDivision of Gastroenterology, Center for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Azienda Ospedaliera San Gerardo · ITUniversity of Milano-Bicocca · ITHumanitas University · ITRWTH Aachen University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune liver diseases (AiLDs) are rare autoimmune conditions of the liver and the biliary tree with unknown etiology and limited treatment options. AiLDs are inherently characterized by a high degree of complexity, which poses great challenges in understanding their etiopathogenesis, developing novel biomarkers and risk-stratification tools, and, eventually, generating new drugs. Artificial intelligence (AI) is considered one of the best candidates to support researchers and clinicians in making sense of biological complexity. In this review, we offer a primer on AI and machine learning for clinicians, and discuss recent available literature on its applications in medicine and more specifically how it can help to tackle major unmet needs in AiLDs.

Indexed as

Autoimmune DiseasesLiver DiseasesArtificial IntelligenceHumansMachine LearningPrecision Medicineautoimmunitydeep learningdigital pathologygenomicsmachine learningpopulation geneticsradiomicswhole-slide digital image analysis

Identifiers

PMID36439097
PMCPMC9691668
OpenAlexW4308910216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.