Evidence map›Paper›PMID 36438938›Full record

ArticleFrontiers in neurology2022

Human periventricular nodular heterotopia shows several interictal epileptic patterns and hyperexcitability of neuronal firing.

Valerio Frazzini, Stephen Whitmarsh, Katia Lehongre, Pierre Yger, Jean-Didier Lemarechal, Bertrand Mathon, Claude Adam, Dominique Hasboun, Virginie Lambrecq, Vincent Navarro

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Valerio FrazziniAP-HP, Pitié Salpêtrière Hospital, Epilepsy Unit and Reference Center for Rare Epilepsies, Paris, France.
Stephen WhitmarshSorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Inserm, CNRS, APHP, Hôpital de la Pitié Salpêtrière, Paris, France.
Katia LehongreSorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Inserm, CNRS, APHP, Hôpital de la Pitié Salpêtrière, Paris, France.
Pierre YgerInstitut de la Vision, INSERM UMRS 968, UPMC UM 80, Paris, France.
Jean-Didier LemarechalSorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Inserm, CNRS, APHP, Hôpital de la Pitié Salpêtrière, Paris, France.
Bertrand MathonSorbonne Université, Institut du Cerveau-Paris Brain Institute-ICM, Inserm, CNRS, APHP, Hôpital de la Pitié Salpêtrière, Paris, France.
Claude AdamAP-HP, Pitié Salpêtrière Hospital, Epilepsy Unit and Reference Center for Rare Epilepsies, Paris, France.
Dominique HasbounAP-HP, Pitié Salpêtrière Hospital, Epilepsy Unit and Reference Center for Rare Epilepsies, Paris, France.
Virginie LambrecqAP-HP, Pitié Salpêtrière Hospital, Epilepsy Unit and Reference Center for Rare Epilepsies, Paris, France.
Vincent NavarroAP-HP, Pitié Salpêtrière Hospital, Epilepsy Unit and Reference Center for Rare Epilepsies, Paris, France.
Centre National de la Recherche Scientifique · FRAssistance Publique – Hôpitaux de Paris · FRInstitut du Cerveau · FRSorbonne Université · FRPitié-Salpêtrière Hospital · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periventricular nodular heterotopia (PNH) is a malformation of cortical development that frequently causes drug-resistant epilepsy. The epileptogenicity of ectopic neurons in PNH as well as their role in generating interictal and ictal activity is still a matter of debate. We report the first

Indexed as

epilepsyhumaninterictalin vivomicroelectrodeperiventricular nodular heterotopiaseizure

Identifiers

PMID36438938
PMCPMC9695411
OpenAlexW4309181219

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.