Evidence map›Paper›PMID 36438885›Full record

ArticleWorld journal of gastrointestinal endoscopy2022

Self-expanding metal stent placement and pathological alterations among obstructive colorectal cancer cases.

Keisuke Kosumi, Kosuke Mima, Kosuke Kanemitsu, Takuya Tajiri, Toru Takematsu, Yuki Sakamoto, Mitsuhiro Inoue, Yuji Miyamoto, Takao Mizumoto, Tatsuo Kubota and 2 more

Open access · diamondAbstract read
In one paragraph

Article in World journal of gastrointestinal endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Keisuke KosumiDepartment of Gastroenterological Surgery, Kumamoto University, Kuma- moto 860-8556, Japan. kosumi-kmm@umin.ac.jp.
Kosuke MimaDepartment of Surgery, National Hospital Organization Kumamoto Medical Center, Kumamoto 860-0008, Japan.
Kosuke KanemitsuDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Honjo 860-8556, Kumamoto, Japan.
Takuya TajiriDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Honjo 860-8556, Kumamoto, Japan.
Toru TakematsuDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Honjo 860-8556, Kumamoto, Japan.
Yuki SakamotoDepartment of Surgery, National Hospital Organization Kumamoto Medical Center, Kumamoto 860-0008, Japan.
Mitsuhiro InoueDepartment of Surgery, National Hospital Organization Kumamoto Medical Center, Kumamoto 860-0008, Japan.
Yuji MiyamotoDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Honjo 860-8556, Kumamoto, Japan.
Takao MizumotoDepartment of Surgery, National Hospital Organization Kumamoto Medical Center, Kumamoto 860-0008, Japan.
Tatsuo KubotaDepartment of Surgery, National Hospital Organization Kumamoto Medical Center, Kumamoto 860-0008, Japan.
Nobutomo MiyanariDepartment of Surgery, National Hospital Organization Kumamoto Medical Center, Kumamoto 860-0008, Japan.
Hideo BabaDepartment of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, Honjo 860-8556, Kumamoto, Japan.
Kumamoto Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExperimental studies suggest that self-expanding metal stents (SEMSs) enhance the aggressive behavior of obstructive colorectal cancer. The influence of SEMS placement on pathological alterations remains to be elucidated.

aimTo determine whether SEMS placement is associated with molecular or pathological features of colorectal carcinoma tissues.

methodsUsing a nonbiased molecular pathological epidemiology database of patients with obstructive colorectal cancers, we examined the association of SEMS placement with molecular or pathological features, including tumor size, histological type, American Joint Committee on Cancer (AJCC)-pTNM stage, and mutation statuses in colorectal cancer tissues compared with the use of transanal tubes. A multivariable logistic regression model was used to adjust for potential confounders.

resultsSEMS placement was significantly associated with venous invasion (

conclusionSEMS placement might be associated with severe venous invasion in colorectal cancer tissue, providing an impetus for further investigations on the pathological alterations by SEMSs in colorectal cancer development.

Indexed as

Bridge to surgeryColorectal carcinomaObstructionStentVenous invasion

Identifiers

PMID36438885
PMCPMC9693689
OpenAlexW4309044315

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.