Evidence map›Paper›PMID 36438799›Full record

ArticleFrontiers in pharmacology2022

A PDE10A inhibitor CPL500036 is a novel agent modulating striatal function devoid of most neuroleptic side-effects.

Mikolaj Matloka, Sylwia Janowska, Piotr Pankiewicz, Sofiya Kokhanovska, Tomasz Kos, Małgorzata Hołuj, Izabela Rutkowska-Wlodarczyk, Krzysztof Abramski, Monika Janicka, Piotr Jakubowski and 9 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 1 country.

Mikolaj MatlokaR&D Centre, Celon Pharma SA, Kazuń Nowy, Poland.
Sylwia JanowskaR&D Centre, Celon Pharma SA, Kazuń Nowy, Poland.
Piotr PankiewiczR&D Centre, Celon Pharma SA, Kazuń Nowy, Poland.
Sofiya KokhanovskaR&D Centre, Celon Pharma SA, Kazuń Nowy, Poland.
Tomasz KosDepartment of Behavioral Neuroscience and Drug Development, Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland.
Małgorzata HołujDepartment of Behavioral Neuroscience and Drug Development, Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland.
Izabela Rutkowska-WlodarczykR&D Centre, Celon Pharma SA, Kazuń Nowy, Poland.
Krzysztof AbramskiR&D Centre, Celon Pharma SA, Kazuń Nowy, Poland.
Monika JanickaR&D Centre, Celon Pharma SA, Kazuń Nowy, Poland.
Piotr JakubowskiR&D Centre, Celon Pharma SA, Kazuń Nowy, Poland.
Maciej ŚwiątkiewiczMossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland.
Marlena Welniak-KaminskaMossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland.
Joanna Hucz-KalitowskaR&D Centre, Celon Pharma SA, Kazuń Nowy, Poland.
Paulina DeraR&D Centre, Celon Pharma SA, Kazuń Nowy, Poland.
Lukasz BojarskiR&D Centre, Celon Pharma SA, Kazuń Nowy, Poland.
Paweł GriebMossakowski Medical Research Institute, Polish Academy of Sciences, Warsaw, Poland.
Piotr PopikDepartment of Behavioral Neuroscience and Drug Development, Maj Institute of Pharmacology, Polish Academy of Sciences, Kraków, Poland.
Maciej WieczorekR&D Centre, Celon Pharma SA, Kazuń Nowy, Poland.
Jerzy PieczykolanR&D Centre, Celon Pharma SA, Kazuń Nowy, Poland.
Celon Pharma (Poland) · PLPolish Academy of Sciences · PLMaj Institute of Pharmacology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CPL500036drug developmentlead characterizationPDE10A inhibitorsafety evaluation

Identifiers

PMID36438799
PMCPMC9681820
OpenAlexW4308722881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.