Evidence map›Paper›PMID 36438687›Full record

ArticleComputational intelligence and neuroscience2022

A Computational Model of Blood D-Dimer, Cystatin C, and CRP Levels Predicts the Risk of Intracranial Aneurysms and their Rupture.

Liang Xing, Haibo Long, Rui Bo, Xue Gou, Yan He, Xing Peng

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in Computational intelligence and neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Mendelian randomization demonstrates a causal link between peripheral circulating acylcarnitines and intracranial aneurysms.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Liang XingDepartment of Neurosurgery, Chongqing Hospital of Traditional Chinese Medicine, No. 6, Panxi Qizhi Road, Jiangbei District, Chongqing 400021, China.
Haibo LongDepartment of Neurosurgery, Chongqing Hospital of Traditional Chinese Medicine, No. 6, Panxi Qizhi Road, Jiangbei District, Chongqing 400021, China.
Rui BoDepartment of Neurosurgery, Chongqing Hospital of Traditional Chinese Medicine, No. 6, Panxi Qizhi Road, Jiangbei District, Chongqing 400021, China.
Xue GouDepartment of Neurosurgery, Chongqing Hospital of Traditional Chinese Medicine, No. 6, Panxi Qizhi Road, Jiangbei District, Chongqing 400021, China.
Yan HeDepartment of Neurosurgery, Chongqing Hospital of Traditional Chinese Medicine, No. 6, Panxi Qizhi Road, Jiangbei District, Chongqing 400021, China.
Xing PengDepartment of Neurosurgery, Chongqing Hospital of Traditional Chinese Medicine, No. 6, Panxi Qizhi Road, Jiangbei District, Chongqing 400021, China.ORCID https://orcid.org/0000-0002-0439-417X
First People's Hospital of Chongqing · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study is to construct a computational model of blood D-dimer, cystatin C, and CRP levels and to predict the risk of intracranial aneurysms and their rupture. Methods: A total of 69 intracranial aneurysms patients were selected as the case group, including 28 cases in the ruptured group and 41 cases in the unruptured group. Another 64 non-intracranial aneurysm patients were selected as the control group. The detection results of serum D-dimer, cystatin C, and CRP were collected. The logistic regression computational model was used to analyze the occurrence and risk factors of intracranial aneurysms. The receiver operating curves (ROC) of serum D-dimer, cystatin C, and C reactive protein (CRP) levels for predicting intracranial aneurysms and their rupture were drawn, and the area under the curve (AUC), sensitivity, and specificity were calculated. Results: The serum levels of D-dimer, cystatin C, and CRP in patients with intracranial aneurysms were significantly higher than those in the control group and the differences were statistically significant ( Conclusion: The combined detection of serum D-dimer, cystatin C, and CRP levels is a very valuable indicator for predicting the occurrence and rupture of intracranial aneurysms, and combined detection can provide scientific evidence-based guidance for clinical prediction of the occurrence and rupture of intracranial aneurysms.

Indexed as

Aneurysm, RupturedC-Reactive ProteinCystatin CFibrin Fibrinogen Degradation ProductsIntracranial AneurysmComputer SimulationHumansModels, CardiovascularPredictive Value of TestsRisk FactorsC-Reactive ProteinCystatin CFibrin Fibrinogen Degradation Productsfibrin fragment D

Identifiers

PMID36438687
PMCPMC9699777
OpenAlexW4309468613

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.