Evidence map›Paper›PMID 36438572›Full record

ArticleFrontiers in cell and developmental biology2022

Detailed characterizations of cranial nerve anatomy in E14.5 mouse embryos/fetuses and their use as reference for diagnosing subtle, but potentially lethal malformations in mutants.

Lukas F Reissig, Stefan H Geyer, Viola Winkler, Ester Preineder, Fabrice Prin, Robert Wilson, Antonella Galli, Catherine Tudor, Jaqueline K White, Timothy J Mohun and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  4. Three-dimensional structural and metric characterisation of cardioids.Frontiers in cell and developmental biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Lukas F ReissigDivision of Anatomy, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
Stefan H GeyerDivision of Anatomy, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
Viola WinklerDivision of Anatomy, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
Ester PreinederDivision of Anatomy, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
Fabrice PrinThe Francis Crick Institute, London, United Kingdom.
Robert WilsonThe Francis Crick Institute, London, United Kingdom.
Antonella GalliWellcome Trust Sanger Institute, Cambridge, United Kingdom.
Catherine TudorWellcome Trust Sanger Institute, Cambridge, United Kingdom.
Jaqueline K WhiteWellcome Trust Sanger Institute, Cambridge, United Kingdom.
Timothy J MohunThe Francis Crick Institute, London, United Kingdom.
Wolfgang J WeningerDivision of Anatomy, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria.
Medical University of Vienna · ATThe Francis Crick Institute · GBWellcome Sanger Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Careful phenotype analysis of genetically altered mouse embryos/fetuses is vital for deciphering the function of pre- and perinatally lethal genes. Usually this involves comparing the anatomy of mutants with that of wild types of identical developmental stages. Detailed three dimensional information on regular cranial nerve (CN) anatomy of prenatal mice is very scarce. We therefore set out to provide such information to be used as reference data and selected mutants to demonstrate its potential for diagnosing CN abnormalities. Digital volume data of 152 wild type mice, harvested on embryonic day (E)14.5 and of 18 mutants of the

Indexed as

cranial nervesdiagnosisE14.5HREMmouse embryophenotypingreference datatopology

Identifiers

PMID36438572
PMCPMC9682249
OpenAlexW4308724050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.