Evidence map›Paper›PMID 36438502›Full record

ArticleTheranostics2022

Fibroblast-specific activation of Rnd3 protects against cardiac remodeling in diabetic cardiomyopathy via suppression of Notch and TGF-β signaling.

Yan Zhang, Yang Cao, Rui Zheng, Zhenyu Xiong, Zhengru Zhu, Fanya Gao, Wanrong Man, Yu Duan, Jie Lin, Xuebin Zhang and 7 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 45 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Yan ZhangDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Yang CaoDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Rui ZhengDepartment of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi'an, China.
Zhenyu XiongDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Zhengru ZhuDepartment of Otolaryngology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Fanya GaoDepartment of General Practice, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Wanrong ManDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Yu DuanDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Jie LinDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Xuebin ZhangDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Dexi WuDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Mengyuan JiangDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Xiao ZhangDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Congye LiDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Xiaoming GuDepartment of Physiology and Pathophysiology, Fourth Military Medical University, Xi'an, China.
Yanhong FanDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Dongdong SunDepartment of Cardiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Xijing Hospital · CNAir Force Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, Type 2Diabetic CardiomyopathiesMyofibroblastsVentricular RemodelingAnimalsDiabetes Mellitus, ExperimentalFibroblastsMiceMice, Transgenicrho GTP-Binding ProteinsTransforming Growth Factor betarho GTP-Binding ProteinsRnd3 protein, mouseTransforming Growth Factor betaCardiac fibroblastCardiac fibrosisCardiac remodelingOxidative stressRho-GTPase

Identifiers

PMID36438502
PMCPMC9691359
OpenAlexW4311932294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.