ArticleTheranostics2022
The landscape of cancer-associated fibroblasts in colorectal cancer liver metastases.
Open access · goldAbstract read
In one paragraph
Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.
- Cancer-associated fibroblasts and their prognostic role in colorectal cancer: review and meta-analysis.Frontiers in oncology · 2025Pooled it
- Spatial transcriptomics differences of histopathological growth patterns in colorectal cancer liver metastases.British journal of cancer · 2026Article
- The Single-Cell and Spatial Transcriptomics Atlas of Epithelial-Fibroblast Interactions in Colorectal Cancer.Digestive diseases and sciences · 2026Article
- Noninvasive molecular imaging signatures of histopathological growth patterns in colorectal cancer liver metastases.Clinical & experimental metastasis · 2026Review
- Addressing multiple facets of ligand-receptor network inference including single-cell proteomics.Nucleic acids research · 2026Article
- YAP-activated lymph node fibroblasts contribute to extracellular matrix remodeling associated with extranodal extension of oral squamous cell carcinoma.The journal of pathology. Clinical research · 2026Article
- Single-cell analysis identifies dysregulated cell type-specific gene programs and intercellular crosstalk underlying colorectal cancer.NPJ precision oncology · 2026Article
- Cancer-associated fibroblasts-derived exosomal circ_0067557 promotes colorectal cancer epithelial-mesenchymal transition via BHLHE40-mediated transcriptional activation of OTUB2.Biology direct · 2026Article
- The extracellular matrix in inflammation and cancer.Molecular biomedicine · 2026Review
- Proteomic profiling of colorectal liver metastases reveals histopathological response-specific molecular signatures of chemotherapy efficacy.Journal of translational medicine · 2026Article
- SPP1 Drives Colorectal Cancer Liver Metastasis and Immunotherapy Resistance by Stimulating CXCL12 Production in Cancer-Associated Fibroblasts.Cancer research · 2026Article
- Article
- Oncolytic reovirus: tumor-microenvironment remodeling, engineering constraints, and translational strategies.Frontiers in immunology · 2026Review
- The Spatiotemporal Heterogeneity of Tumor-Associated Stromal Cells: Reprogramming Plasticity to Unlock Precision Cancer Immunotherapy.Cancer communications (London, England) · 2026Review
- Multipathway pharmacological interventions targeting liver-derived immune resistance in colorectal cancer liver metastasis.Frontiers in immunology · 2026Review
- CRCs-CAFs crosstalk-targeted nano-delivery system reprograms tumor microenvironment for oxaliplatin resistance reversing and liver metastasis inhibition in colorectal cancer.Bioactive materials · 2025Article
- Single-cell insights into tumor microenvironment heterogeneity and plasticity: transforming precision therapy in gastrointestinal cancers.Journal of experimental & clinical cancer research : CR · 2025Review
- Review
- SMYD3-CDCP1 Axis Drives EMT and CAF Activation in Colorectal Cancer and Is Targetable for Oxaliplatin Sensitization.Biomedicines · 2025Article
- Cancer‑associated fibroblasts in human malignancies, with a particular emphasis on sarcomas (Review).International journal of oncology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 4 institutions in 2 countries.
Ambre GiguelayInstitut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
Evgenia TurtoiInstitut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
Lakhdar KhelafDepartment of Pathology, Institut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
Guillaume TosatoInstitut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
Ikrame DadiInstitut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
Tommy ChastelInstitut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
Marie-Alix PoulInstitut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
Marine PratlongBiocampus, CNRS, INSERM, Université de Montpellier, Montpellier, France.
Stefan NicolescuInstitut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
Dany SeveracBiocampus, CNRS, INSERM, Université de Montpellier, Montpellier, France.
Antoine AdenisDepartment of Medical Oncology, Institut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
Olivia SgarburaDepartment of Surgery, Institut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
Sébastien CarrèreDepartment of Surgery, Institut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
Philippe RouanetDepartment of Surgery, Institut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
François QuenetDepartment of Surgery, Institut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
Marc YchouDepartment of Medical Oncology, Institut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
Didier PourquierInstitut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
Pierre-Emmanuel ColomboBiocampus, CNRS, INSERM, Université de Montpellier, Montpellier, France.
Andrei TurtoiInstitut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
Jacques ColingeInstitut régional du Cancer de Montpellier (ICM)-Val d'Aurelle, Montpellier, France.
Inserm · FRInstitut de Recherche en Cancérologie de Montpellier · FRInstitut Regional du Cancer de MontpellierUniversité de Montpellier · FR
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Cancer-Associated FibroblastsColorectal NeoplasmsLiver NeoplasmsFibroblastsHumansLatent TGF-beta Binding ProteinsTumor MicroenvironmentLatent TGF-beta Binding ProteinsLTBP2 protein, humanCAFliver metastasisLTBP2.single-celltumor microenvironment
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.