Evidence map›Paper›PMID 36438486›Full record

ArticleTheranostics2022

Hippocalcin-Like 1 blunts liver lipid metabolism to suppress tumorigenesis via directly targeting RUVBL1-mTOR signaling.

Tao Chen, Zhiqing Yuan, Zhou Lei, Jinlin Duan, Junyan Xue, Ting Lu, Guouan Yan, Lei Zhang, Yanfeng Liu, Qiwei Li and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Tao ChenUnited International Laboratory, Department of Clinical Laboratory, Sixth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Zhiqing YuanDepartment of Biliary-Pancreatic Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Zhou LeiDepartment of Hepatobiliary Surgery, First Affiliated Hospital of Bengbu Medical College, Bengbu, 233000, Anhui Province, China.
Jinlin DuanDepartment of Pathology Affiliated Tongren Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China.
Junyan XueUnited International Laboratory, Department of Clinical Laboratory, Sixth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Ting LuUnited International Laboratory, Department of Clinical Laboratory, Sixth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Guouan YanInstitutes of Biomedical Sciences of Shanghai Medical School, Fudan University, Shanghai, China.
Lei ZhangInstitutes of Biomedical Sciences of Shanghai Medical School, Fudan University, Shanghai, China.
Yanfeng LiuRenji-Med-X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Qiwei LiDepartment of Biliary-Pancreatic Surgery, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Yonglong ZhangUnited International Laboratory, Department of Clinical Laboratory, Sixth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Renji Hospital · CNShanghai Medical College of Fudan University · CNShanghai Jiao Tong University · CNTongren Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAnimalsATPases Associated with Diverse Cellular ActivitiesCalcium-Binding ProteinsCarcinogenesisCarrier ProteinsCell Transformation, NeoplasticDNA HelicasesHippocalcinHumansLipid MetabolismLipidsMammalsMechanistic Target of Rapamycin Complex 1MiceATPases Associated with Diverse Cellular ActivitiesCalcium-Binding ProteinsCarrier ProteinsDNA HelicasesHippocalcinHPCAL1 protein, humanLipidsMechanistic Target of Rapamycin Complex 1MTOR protein, humanmTOR protein, mouseNerve Tissue ProteinsNeurocalcinRUVBL1 protein, humanRUVBL1 protein, mouseTOR Serine-Threonine KinasesVILIP-3 protein, mouseCholesterol synthesisfatty acid biosynthesisHippocalcin-Like 1mTOR addictionRUVBL1

Identifiers

PMID36438486
PMCPMC9691343
OpenAlexW4311928118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.