Evidence map›Paper›PMID 36438483›Full record

ArticleTheranostics2022

TIMM44 is a potential therapeutic target of human glioma.

Yi-Zhuo Guo, Gang Chen, Man Huang, Yin Wang, Yuan-Yuan Liu, Qin Jiang, Cong Cao, Fang Liu

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yi-Zhuo GuoInstitute of Neuroscience, Soochow University, Suzhou, and Department of Neurosurgery, The affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, China.
Gang ChenDepartment of Neurosurgery, the First Affiliated Hospital of Soochow University, Suzhou, China.
Man HuangDepartment of Oncology, Dushu Lake Hospital Affiliated of Soochow University, Suzhou, China.
Yin WangDepartment of Radiotherapy and Oncology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, China.
Yuan-Yuan LiuDepartment of Radiotherapy and Oncology, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, China.
Qin JiangThe Fourth School of Clinical Medicine, The Affiliated Eye Hospital, Nanjing Medical University, Nanjing, China.
Cong CaoInstitute of Neuroscience, Soochow University, Suzhou, and Department of Neurosurgery, The affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, China.
Fang LiuInstitute of Neuroscience, Soochow University, Suzhou, and Department of Neurosurgery, The affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, China.
Jiangsu University · CNSecond Affiliated Hospital of Nanjing Medical University · CNSoochow University · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TIMM44 (translocase of inner mitochondrial membrane 44) is essential for the maintenance of mitochondrial functions. Bioinformatics studies and results from the local high-grade glioma tissues showed that

Indexed as

GliomaAdenosine TriphosphateAnimalsCell ProliferationCell SurvivalHumansMetalloendopeptidasesMiceMitochondrial Membrane Transport ProteinsMitochondrial Precursor Protein Import Complex ProteinsRNA, Small InterferingAdenosine TriphosphateMetalloendopeptidasesMitochondrial Membrane Transport ProteinsMitochondrial Precursor Protein Import Complex ProteinsRNA, Small InterferingTIMM44 protein, humanTimm44 protein, mouseYme1l1 protein, mouseGliomaMitochondriaTherapeutic targetTIMM44

Identifiers

PMID36438483
PMCPMC9691352
OpenAlexW4310707630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.