Evidence map›Paper›PMID 36438076›Full record

ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2022

Association between physical activity and serum liver aminotransferases in Southwestern Iran: A Cross-sectional study.

Sajad Badiei, Seyed Jalal Hashemi, Abdolrahim Masjedizadeh, Jalal Sayyah, Zahra Mohammadi, Sanam Hariri, Farnaz Hashemi, Zahra Rahimi, Leila Danehchin, Farhad Abolnezhadian and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Sajad BadieiAlimentary Tract Research Center, Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Seyed Jalal HashemiAlimentary Tract Research Center, Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Abdolrahim MasjedizadehAlimentary Tract Research Center, Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Jalal SayyahAlimentary Tract Research Center, Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Zahra MohammadiLiver and Pancreatobiliary Diseases Research Center, Digestive Disease Research Institute, Tehran, Iran.
Sanam HaririLiver and Pancreatobiliary Diseases Research Center, Digestive Disease Research Institute, Tehran, Iran.
Farnaz HashemiLiver and Pancreatobiliary Diseases Research Center, Digestive Disease Research Institute, Tehran, Iran.
Zahra RahimiDepartment of Biostatistics and Epidemiology, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Leila DanehchinDepartment of Medicine, Faculty of Medicine, Behbahan Faculty of Medical Sciences, Behbahan, Iran.
Farhad AbolnezhadianDepartment of Pediatrics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Reza MalihiDepartment of Basic Sciences, School of Medicine, Abadan University of Medical Sciences, Abadan, Iran.
Yousef ParidarDepartment of Internal Medicine, School of Medicine, Dezful University of Medical Sciences, Dezful, Iran.
Seyyed Ali MardAlimentary Tract Research Center, Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Bahman CheraghianDepartment of Biostatistics and Epidemiology, School of Public Health, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Hossein PoustchiLiver and Pancreatobiliary Diseases Research Center, Digestive Disease Research Institute, Tehran, Iran.
Ali Akbar ShayestehAlimentary Tract Research Center, Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Ahvaz Jundishapur University of Medical Sciences · IRDigestive Disease Research InstituteDezful University of Medical Sciences · IRIsfahan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The main aim of the present study is to investigate the independent association objectively measured level of physical activity (PA) and serum concentration of liver aminotransferases (alanine aminotransferase [ALT] and aspartate aminotransferase [AST]) among seemingly healthy individuals. Materials and Methods: The current secondary study was conducted in the framework of Khuzestan Comprehensive Health Study, a large population-based multicentric cross-sectional study, conducted between 2016 and 2019 on 18,966 individuals living in Khuzestan province, southwestern Iran. International PA Questionnaire was used for evaluating PA levels, and participants were divided into three groups: low, moderate, and high PA, and ALT and AST were compared between these groups. Results: The mean ± standard deviation age of participants was 38.65 ± 11.40 years. The majority of participants were female (71%). The mean concentration of ALT in total sample was 18.22 ± 13.06 (male: 23.65 ± 16.26 and female: 15.57 ± 10.06), while the mean concentration of ALT in total sample was 19.61 ± 8.40 (male: 22.44 ± 10.03 and female: 18.23 ± 7.08). A statistically significant inverse correlation was found between AST ( Conclusion: The current study based on large sample showed that PA had a statistically negative association with the concentration of liver aminotransferases in the seemingly healthy individuals; however, the observed associations were weak. People in the lowest levels of PA had the highest levels of ALT and AST.

Indexed as

Alanine aminotransferaseaspartate aminotransferaseliver aminotransferasephysical activity

Identifiers

PMID36438076
PMCPMC9693751
OpenAlexW4310461543

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.