Evidence map›Paper›PMID 36437994›Full record

ArticleFrontiers in aging neuroscience2022

The relationship between Alzheimer's disease and intestinal microflora structure and inflammatory factors.

Su-Shan Wang, Xiao-Hui Li, Ping Liu, Jing Li, Li Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  16. Oral Administration ofAntioxidants (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Su-Shan WangDepartment of General Practice, The Sixth Medical Center of PLA General Hospital, Beijing, China.
Xiao-Hui LiSix Health Care Department, The Sixth Medical Center of PLA General Hospital, Beijing, China.
Ping LiuDepartment of General Practice, The Sixth Medical Center of PLA General Hospital, Beijing, China.
Jing LiDepartment of General Practice, The Sixth Medical Center of PLA General Hospital, Beijing, China.
Li LiuDepartment of General Practice, The Sixth Medical Center of PLA General Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To analyze the structural characteristics of intestinal microflora and changes of serum inflammatory factors of the Alzheimer's disease, and to explore the relationship between them and dementia, we selected 30 patients in the AD group and 30 patients in the normal group, and collected stool samples to analyze the intestinal flora structure characteristics of the two groups of patients, and statistically analyzed the inflammatory cytokines TNF-α, IL-1β, IL-6, and IL-8 by ELISA from the venous blood of the two groups. The results show that the dominant

Indexed as

Alzheimer’s diseaseIL-6inflammatory factorsintestinal microfloraTNF-α

Identifiers

PMID36437994
PMCPMC9681782

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.