Evidence map›Paper›PMID 36437952›Full record

ArticleFrontiers in genetics2022

Identification of COVID-19 severity biomarkers based on feature selection on single-cell RNA-Seq data of CD8

Jian Lu, Mei Meng, XianChao Zhou, Shijian Ding, KaiYan Feng, Zhenbing Zeng, Tao Huang, Yu-Dong Cai

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Jian LuDepartment of Mathematics, School of Sciences, Shanghai University, Shanghai, China.
Mei MengState Key Laboratory of Oncogenes and Related Genes, Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
XianChao ZhouState Key Laboratory of Oncogenes and Related Genes, Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shijian DingSchool of Life Sciences, Shanghai University, Shanghai, China.
KaiYan FengDepartment of Computer Science, Guangdong AIB Polytechnic College, Guangzhou, China.
Zhenbing ZengDepartment of Mathematics, School of Sciences, Shanghai University, Shanghai, China.
Tao HuangCAS Key Laboratory of Computational Biology, Bio-Med Big Data Center, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Science, Shanghai, China.
Yu-Dong CaiSchool of Life Sciences, Shanghai University, Shanghai, China.
Shanghai University · CNGuangdong Polytechnic Normal University · CNShanghai Institute of Nutrition and Health · CNShanghai Jiao Tong University · CNState Key Laboratory of Oncogene and Related Genes · CNUniversity of Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global outbreak of the COVID-19 epidemic has become a major public health problem. COVID-19 virus infection triggers a complex immune response. CD8

Indexed as

CD8+ T cellCOVID-19feature selectionseveritysingle-cell

Identifiers

PMID36437952
PMCPMC9682094
OpenAlexW4308722092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.