Evidence map›Paper›PMID 36437873›Full record

ArticleiScience2022

CD47 restricts antiviral function of alveolar macrophages during influenza virus infection.

Christina Wenzek, Philine Steinbach, Florian Wirsdörfer, Kathrin Sutter, Julia D Boehme, Robert Geffers, Robert Klopfleisch, Dunja Bruder, Verena Jendrossek, Jan Buer and 2 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Christina WenzekInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen 45147, Germany.
Philine SteinbachInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen 45147, Germany.
Florian WirsdörferInstitute of Cell Biology (Cancer Research), University Hospital Essen, Essen 45147, Germany.
Kathrin SutterInstitute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen 45147, Germany.
Julia D BoehmeImmune Regulation Group, Helmholtz Centre for Infection Research (HZI), Braunschweig 38124, Germany.
Robert GeffersGenome Analytics, Helmholtz Centre for Infection Research (HZI), Braunschweig 38124, Germany.
Robert KlopfleischInstitute of Veterinary Pathology, Freie Universitaet Berlin, Berlin 14163, Germany.
Dunja BruderImmune Regulation Group, Helmholtz Centre for Infection Research (HZI), Braunschweig 38124, Germany.
Verena JendrossekInstitute of Cell Biology (Cancer Research), University Hospital Essen, Essen 45147, Germany.
Jan BuerInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen 45147, Germany.
Astrid M WestendorfInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen 45147, Germany.
Torben KnuschkeInstitute of Medical Microbiology, University Hospital Essen, University of Duisburg-Essen, Essen 45147, Germany.
University of Duisburg-Essen · DEHelmholtz Centre for Infection Research · DEEssen University Hospital · DEFreie Universität Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD47 is an ubiquitously expressed surface molecule with significant impact on immune responses. However, its role for antiviral immunity is not fully understood. Here, we revealed that the expression of CD47 on immune cells seemed to disturb the antiviral immune response as CD47-deficient mice (CD47

Indexed as

ImmunologyVirology

Identifiers

PMID36437873
PMCPMC9682344
OpenAlexW4308804847

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.