Evidence map›Paper›PMID 36437762›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2024

Deep learning prediction of stroke thrombus red blood cell content from multiparametric MRI.

Spencer D Christiansen, Junmin Liu, Maria Bres Bullrich, Manas Sharma, Melfort Boulton, Sachin K Pandey, Luciano A Sposato, Maria Drangova

Abstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Differential Diagnostic Value of Machine Learning-Based Models for Embolic Stroke.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Spencer D ChristiansenRobarts Research Institute, Western University, London, Ontario, Canada.ORCID 0000-0002-9497-6789
Junmin LiuRobarts Research Institute, Western University, London, Ontario, Canada.
Maria Bres BullrichDepartment of Clinical Neurological Sciences, Western University, London, Ontario, Canada.
Manas SharmaDepartment of Medical Imaging, Western University, London, Ontario, Canada.
Melfort BoultonDepartment of Clinical Neurological Sciences, Western University, London, Ontario, Canada.
Sachin K PandeyDepartment of Medical Imaging, Western University, London, Ontario, Canada.
Luciano A SposatoDepartment of Clinical Neurological Sciences, Western University, London, Ontario, Canada.
Maria DrangovaRobarts Research Institute, Western University, London, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThrombus red blood cell (RBC) content has been shown to be a significant factor influencing the efficacy of acute ischemic stroke treatment. In this study, our objective was to evaluate the ability of convolutional neural networks (CNNs) to predict ischemic stroke thrombus RBC content using multiparametric MR images. MATERIALS AND

methodsRetrieved stroke thrombi were scanned

resultsThe CNN predicted thrombus RBC content with an accuracy of 62% (95% CI 48-76%) when trained on the original dataset and improved to 72% (95% CI 60-84%) on the augmented dataset. The network classified thrombi as RBC-rich or poor with an accuracy of 71% (95% CI 58-84%) and an area under the curve of 0.72 (95% CI 0.57-0.87) when trained on the original dataset and improved to 80% (95% CI 69-91%) and 0.84 (95% CI 0.73-0.95), respectively, on the augmented dataset.

conclusionsThe CNN was able to accurately predict thrombus RBC content using multiparametric MR images, and could provide a means to guide treatment strategy in acute ischemic stroke.

Indexed as

Deep LearningErythrocytesIschemic StrokeMultiparametric Magnetic Resonance ImagingAgedFemaleHumansIntracranial ThrombosisMaleMiddle AgedNeural Networks, ComputerStrokeThrombosisdeep learningIschemic strokemachine learningMRIRBCthrombus imaging

Identifiers

PMID36437762
PMCPMC11483724

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.