Evidence map›Paper›PMID 36437532›Full record

SynthesisJournal of dental research2023

Novel Genetic Determinants of Dental Maturation in Children.

O Grgic, V Prijatelj, A Dudakovic, S Vucic, B Dhamo, K Trajanoska, C Monnereau, M Zrimsek, K M Gautvik, S Reppe and 12 more

Open access · greenAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of dental research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 12 institutions in 8 countries.

O GrgicDepartment of Oral and Maxillofacial Surgery, ErasmusMC, Rotterdam, The Netherlands.
V PrijateljDepartment of Oral and Maxillofacial Surgery, ErasmusMC, Rotterdam, The Netherlands.ORCID 0000-0002-9463-3962
A DudakovicDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
S VucicDepartment of Oral and Maxillofacial Surgery, ErasmusMC, Rotterdam, The Netherlands.ORCID 0000-0003-3352-3900
B DhamoDepartment of Oral and Maxillofacial Surgery, ErasmusMC, Rotterdam, The Netherlands.ORCID 0000-0002-5537-067X
K TrajanoskaDepartment of Human Genetics McGill University, Montréal, Québec, Canada.
C MonnereauThe Generation R Study, ErasmusMC, Rotterdam, The Netherlands.
M ZrimsekDepartment of Pathology, Medical University of Vienna, Vienna, Austria.ORCID 0000-0003-4950-1386
K M GautvikDepartment of Medical Biochemistry, Oslo University Hospital, Oslo, Norway.
S ReppeDepartment of Medical Biochemistry, Oslo University Hospital, Oslo, Norway.
E ShimizuDepartment of Oral Biology, Rutgers School of Dental Medicine, Newark, NJ, USA.
S HaworthDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID 0000-0001-7793-7326
N J TimpsonDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
V W V JaddoeThe Generation R Study, ErasmusMC, Rotterdam, The Netherlands.
M-R JarvelinFaculty of Medicine, Center for Life Course Health Research, University of Oulu, Oulu, Finland.
D EvansMRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.
A G UitterlindenThe Generation R Study, ErasmusMC, Rotterdam, The Netherlands.
E M OngkosuwitoDentistry, Section Orthodontics and Craniofacial Biology, Radboud University Medical Center, Nijmegen, The Netherlands.
A J van WijnenDepartment of Biochemistry, University of Vermont, Burlington, VT, USA.
C Medina-GomezThe Generation R Study, ErasmusMC, Rotterdam, The Netherlands.
F RivadeneiraDepartment of Oral and Maxillofacial Surgery, ErasmusMC, Rotterdam, The Netherlands.
E B WolviusDepartment of Oral and Maxillofacial Surgery, ErasmusMC, Rotterdam, The Netherlands.
Erasmus MC · NLOslo University Hospital · NOImperial College London · GBMayo Clinic in Arizona · USMcGill University · CAMedical University of Vienna · ATRadboud University Nijmegen · NLRutgers, The State University of New Jersey · USThe University of Queensland · AUUniversity of Bristol · GBUniversity Of Bristol Dental Hospital · GBUniversity of Vermont · US

Funding

Role of force regulated nuclear structure in expression of osteogenesisR01AR075803 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUBIN, JANET E · 2020 to 2024
$2.4M
Cancer Research UK C18281/A29019Department of Health BRC-1215-2001Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_PC_19009Medical Research Council MC_UU_00011/1NIAMS NIH HHS R01 AR075803Wellcome Trust 202802/Z/16/ZWellcome Trust 217065/Z/19/Z
6 · The paper itself

Abstract

Dental occlusion requires harmonious development of teeth, jaws, and other elements of the craniofacial complex, which are regulated by environmental and genetic factors. We performed the first genome-wide association study (GWAS) on dental development (DD) using the Demirjian radiographic method. Radiographic assessments from participants of the Generation R Study (primary study population,

Indexed as

Genome-Wide Association StudyToothAllelesAnimalsChildGenetic LociGenetic Predisposition to DiseaseHumansInfantMicePolymorphism, Single Nucleotidechild healthgene expressionGWASodontogenesistooth calcificationtooth eruption

Identifiers

PMID36437532
PMCPMC10083589
OpenAlexW4310262032

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.