Evidence map›Paper›PMID 36437468›Full record

ArticleEuropean journal of medical research2022

The combination of olive oil and Lepidium sativum improves the deleterious effects resulting from dexamethasone-induced osteoporosis in rats.

Dalia M Badary, Heba A Galal, Mahmoud H Abdelraheim, Mohamed I Sedeek, Nesma M Mohamed, Zakaria Y Abd Elmageed, Magda M Y Farrag

Open access · goldAbstract read
In one paragraph

Article in European journal of medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. [Basic Research on the Microstructure of Rat Bones in the High-Altitude Environment of Qinghai-Tibet Plateau].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Dalia M BadaryPathology Department, Faculty of Medicine, Assiut University, Asyût, 71526, Egypt. daliabadary@aun.edu.eg.
Heba A GalalPharmacology Department, Faculty of Veterinary Medicine, Assiut University, Asyût, 71526, Egypt.
Mahmoud H AbdelraheimPharmacology Department, Faculty of Medicine, Assiut University, Asyût, 71526, Egypt.
Mohamed I SedeekClinical Pathology Department, Faculty of Medicine, Assiut University, Asyût, 71526, Egypt.
Nesma M MohamedPharmacognosy Department, Faculty of Pharmacy, Assiut University, Asyût, 71526, Egypt.
Zakaria Y Abd ElmageedDepartment of Pharmacology, Edward Via College of Osteopathic Medicine, University of Louisiana at Monroe, Monroe, LA, 71203, USA.
Magda M Y FarragPharmacology Department, Faculty of Medicine, Assiut University, Asyût, 71526, Egypt.
Assiut University · EGUniversity of Louisiana at Monroe · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOsteoporosis is characterized by deterioration of bone microarchitecture and reduced bone mass and can increase the risk of fracture. To reduce this risk, the aim of this study was to compare the combination effects of olive oil and Lepidium sativum compared to the conventional drug therapy alendronate.

methodsOsteoporosed-induced rat model was established by administration of dexamethasone in female adult albino rats. The serum level of Ca

resultsOur results showed that a combination of olive oil and Lepidium sativum had a beneficial therapeutic effect in the treatment of osteoporosis as compared to alendronate therapy. This was demonstrated by increase of serum Ca

conclusionWe concluded that the administration of a combination of olive oil and Lepidium sativum improves bone mineral health and intensity and reduces the risk of osteoporosis in a rat model.

Indexed as

Lepidium sativumOsteoporosisAlendronateAnimalsDexamethasoneOlive OilOsteocalcinOsteopontinRatsAlendronateDexamethasoneOlive OilOsteocalcinOsteopontinAlendronateLepidium sativumOsteopontinOsteoporosis, rats, olive oil

Identifiers

PMID36437468
PMCPMC9703703
OpenAlexW4310264943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.