ReviewOdontology2023
Psychological stress: neuroimmune roles in periodontal disease.
Review in Odontology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 28 citations in OpenAlex.
- Peri-implant crevicular fluid stress-related biomarkers and psychometric scores in peri-implant health and disease.Clinical oral investigations · 2026Article
- Depressive symptoms, oral health behaviors, and self-reported oral health conditions among Chinese university students: a cross-sectional study.Frontiers in oral health · 2026Article
- Salivary chromogranin A levels in periodontal health status: a cross-sectional study evaluating clinical and psychological associations.BMC oral health · 2025Article
- Psychological Stress Reduces the Effectiveness of Periodontal Treatment: A Systematic Review.Journal of clinical medicine · 2025Review
- The impact of psychological stress on salivary cortisol levels in periodontitis patients: a case-control study.BMC oral health · 2025Article
- Human oral microbiome and its influence on mental health and brain disorders.AIMS microbiology · 2025Review
- The relationship of stress level and periodontal tissue health in soldiers from Kodam Jaya: a cross-sectional study.Frontiers in oral health · 2025Article
- Assessing oral and toothbrush microbial profiles among high-altitude individuals with and without periodontal disease: a case-control study.BMC oral health · 2024Article
- Article
- Periodontal disease increases the severity of chronic obstructive pulmonary disease: a Mendelian randomization study.BMC pulmonary medicine · 2024Article
- The Relationship Between Mental Health and Periodontal Disease: Insights from NHANES Data.F1000Research · 2024Article
- Does the guideline-based physical activity level for cardiovascular health also benefit periodontal health?Journal of dental sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Periodontitis is a chronic inflammatory disease that starts with pathogenic bacteria and is mediated by a combination of multiple factors. Psychosomatic factors are considered to be one of the most critical risk factors for periodontal disease. Psychological stress may threaten periodontal immune homeostasis in multiple ways by affecting the hypothalamic-pituitary-adrenal cortex system, the locus ceruleus-sympathetic-adrenal medulla system, and the peptidergic nervous system. In this review, we outline the complex role of psychological stress in promoting the development of periodontal disease, focusing on the effects of stress on flora metabolism, tissue inflammation, and alveolar bone homeostasis. At the same time, we broadly and deeply summarize the potential mechanisms of psychological stress-induced periodontal disease, emphasize the importance of neuroimmune modulation for periodontal health, and expect to provide a new perspective for periodontal science based on psychoneuroimmunology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.