Evidence map›Paper›PMID 36437389›Full record

ArticleThe patient2023

Patients' Preferences for Connected Insulin Pens: A Discrete Choice Experiment Among Patients with Type 1 and Type 2 Diabetes.

Jaein Seo, Sebastian Heidenreich, Esraa Aldalooj, Jiat Ling Poon, Erik Spaepen, Elizabeth L Eby, Rachel S Newson

Open access · hybridAbstract read
In one paragraph

Article in The patient, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Connected Insulin Pens and Pen Caps: Expanding Diabetes Technology Access and Adoption.Diabetes spectrum : a publication of the American Diabetes Association · 2025
    Article
  8. Review
  9. Article
  10. Physician Perceptions of Dose Escalation for Type 2 Diabetes Medications in the United States.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
    Article
  11. Out of Sight, Out of Mind: A Call to Action for the Treatment of Hypoglycemia.Clinical diabetes : a publication of the American Diabetes Association · 2024
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jaein SeoPatient-Centered Research, Evidera, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-1486-5876
Sebastian HeidenreichPatient-Centered Research, Evidera, London, UK.ORCID http://orcid.org/0000-0002-1909-5770
Esraa AldaloojPatient-Centered Research, Evidera, London, UK.ORCID http://orcid.org/0000-0002-2786-1041
Jiat Ling PoonValue, Evidence, and Outcomes, Eli Lilly and Co, Indianapolis, IN, USA.ORCID http://orcid.org/0000-0001-7038-2102
Erik SpaepenHaaPACS GmbH, Schriesheim, Germany.ORCID http://orcid.org/0000-0001-7590-7844
Elizabeth L EbyValue, Evidence, and Outcomes, Eli Lilly and Co, Indianapolis, IN, USA.ORCID http://orcid.org/0000-0003-3896-6583
Rachel S NewsonMedical Affairs, Eli Lilly and Co., Sydney, Australia. newson_rachel@lilly.com.ORCID http://orcid.org/0000-0002-2653-5797
Eli Lilly (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study quantified how people with diabetes value the unique features of connected insulin pens and related mobile apps, and the underlying reasons for preferring connected versus non-connected insulin pens.

methodsA discrete choice experiment (DCE) was conducted in the USA and UK to elicit preferences of adults (≥ 18 years) with type 1 or 2 diabetes for attributes of insulin pens. Attributes included device type, dosing support, glucose monitoring, additional app features, and data sharing. Relative attribute importance (RAI) scores were calculated to capture the relative importance of an attribute. Predicted choice probabilities were obtained to compare different profiles for connected and non-connected insulin pens.

resultsThe DCE was completed by 540 participants (58.9% male; 90.7% Caucasian; mean age, 58.3 years; 69.4% type 2 diabetes). Participants most valued the possibility of using a connected insulin pen with dosing support and automated dose logging (RAI = 39.9%), followed by automatic transfer of glucose levels (RAI = 29.0%), additional features of tracking diet and physical activity (RAI = 14.6%), data sharing (RAI = 13.6%), and device type (RAI = 2.9%). All profiles of connected insulin pens were preferred over a non-connected pen (p < 0.001), and pen profiles with advanced features were preferred over those without (p < 0.001). Preferences differed by age but not diabetes type, country of residence, or insulin regimen.

conclusionPeople with diabetes in the USA and UK prefer connected over non-connected insulin pens due largely to the availability of automated logging of dose and glucose levels.

Indexed as

Diabetes Mellitus, Type 2AdultBlood GlucoseBlood Glucose Self-MonitoringFemaleHumansHypoglycemic AgentsInsulinMaleMiddle AgedPatient PreferenceBlood GlucoseHypoglycemic AgentsInsulin

Identifiers

PMID36437389
PMCPMC9911509
OpenAlexW4310172345

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.