Evidence map›Paper›PMID 36437190›Full record

ArticleCytotherapy2023

Allogeneic cord blood regulatory T cells can resolve lung inflammation.

Mi-Ae Lyu, Meixian Huang, Ke Zeng, Li Li, Joseph D Khoury, Mitsutaka Nishimoto, Hongbing Ma, Tara Sadeghi, Siddhartha Mukherjee, Arthur S Slutsky and 2 more

Open access · greenAbstract read
In one paragraph

Article in Cytotherapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Review
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  4. Article
  5. Article
  6. Article
  7. Investigational drugs in early phase trials for myelofibrosis.Expert opinion on investigational drugs · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. CD4Frontiers in immunology · 2023
    Review
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Mi-Ae LyuDepartment of Lymphoma/Myeloma, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Meixian HuangDepartment of Lymphoma/Myeloma, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Ke ZengDepartment of Lymphoma/Myeloma, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Li LiDepartment of Lymphoma/Myeloma, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Joseph D KhouryDepartment of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Mitsutaka NishimotoDepartment of Lymphoma/Myeloma, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Hongbing MaDepartment of Lymphoma/Myeloma, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Tara SadeghiCellenkos Inc, Houston, Texas, USA.
Siddhartha MukherjeeDivision of Hematology/Oncology, Department of Medicine, New York-Presbyterian Hospital, Columbia University Irving Medical Center, New York, New York, USA.
Arthur S SlutskyKeenan Research Center, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Unity Health Toronto, University of Toronto, Toronto, Canada.
Christopher R FlowersDepartment of Lymphoma/Myeloma, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Simrit ParmarDepartment of Lymphoma/Myeloma, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA. Electronic address: simrit.parmar@gmail.com.
The University of Texas MD Anderson Cancer Center · USNewYork–Presbyterian Hospital · USSt. Michael's Hospital · CA

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI DIANE BODURKA · 1985 to 2026
$290.8M
Mentored Patient Oriented Research in LymphomaK24CA208132 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI FLOWERS, CHRISTOPHER R · 2016 to 2020
$822k
NCI NIH HHS K24 CA208132NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

BACKGROUND

aimsCD4

resultsEx vivo-expanded UCB Tregs exhibited a unique phenotype with co-expression of CD45RA

conclusionsUCB Treg adoptive therapy is a promising therapeutic strategy for treatment of lung injury.

Indexed as

Hematopoietic Stem Cell TransplantationLung InjuryPneumoniaCD8-Positive T-LymphocytesFetal BloodHumansInflammationLeukocyte Common AntigensT-Lymphocytes, RegulatoryLeukocyte Common Antigensadoptive cell therapycord bloodlung inflammationlung injuryregulatory T cells

Identifiers

PMID36437190
PMCPMC12481963
OpenAlexW4309971359

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.