Evidence map›Paper›PMID 36437111›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Modulating Nanozyme-Based Nanomachines via Microenvironmental Feedback for Differential Photothermal Therapy of Orthotopic Gliomas.

Na Yin, Yinghui Wang, Ying Huang, Yue Cao, Longhai Jin, Jianhua Liu, Tianqi Zhang, Shuyan Song, Xiaogang Liu, Hongjie Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Na YinState Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, China.
Yinghui WangState Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, China.
Ying HuangSchool of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei, Anhui, 230026, China.
Yue CaoDepartment of Neurosurgery, The First Hospital of Jilin University, Changchun, Jilin, 130061, China.
Longhai JinDepartment of Radiology, The Second Hospital of Jilin University, Changchun, Jilin, 130041, China.
Jianhua LiuDepartment of Radiology, The Second Hospital of Jilin University, Changchun, Jilin, 130041, China.
Tianqi ZhangDepartment of Radiology, The Second Hospital of Jilin University, Changchun, Jilin, 130041, China.
Shuyan SongState Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, China.
Xiaogang LiuDepartment of Chemistry, National University of Singapore, Singapore, 117543, Singapore.
Hongjie ZhangState Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, China.ORCID 0000-0001-5433-8611
University of Science and Technology of China · CNSecond Affiliated Hospital of Jilin University · CNJilin University · CNNational University of Singapore · SG

Funding

National Key R&D Program of China 2020YFA0712102National Natural Science Foundation of China 21834007National Natural Science Foundation of China 22020102003National Natural Science Foundation of China 52022094National Natural Science Foundation of China 5207214National Natural Science Foundation of China 82071981Program of Science and Technology Development Plan of Jilin Province of China 20210101111JCProgram of Science and Technology Development Plan of Jilin Province of China 20210101287JCYouth Innovation Promotion Association of Chinese Academy of Sciences 2019232
6 · The paper itself

Abstract

Gliomas are common and refractory primary tumors closely associated with the fine structures of the brain. Photothermal therapy (PTT) has recently shown promise as an effective treatment for gliomas. However, nonspecific accumulation of photothermal agents may affect adjacent normal brain structures, and the inflammatory response induced during PTT may result in an increased risk of brain tumor recurrence or metastasis. Here, the design and fabrication of an intelligent nanomachine is reported based on Gd

Indexed as

GliomaPhotothermal TherapyFeedbackHumansInflammationNeoplasm Recurrence, LocalTumor Microenvironmentinflammationnanomachinesnanozymeorthotopic gliomaphotothermal therapy

Identifiers

PMID36437111
PMCPMC9875674
OpenAlexW4310277280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.