Evidence map›Paper›PMID 36437107›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

In Vivo Anchoring Bis-Pyrene Probe for Molecular Imaging of Early Gastric Cancer by Endoscopic Techniques.

Qiang Luo, Chaoqiang Fan, Wang Ying, Xue Peng, Yiyang Hu, Zhaohui Luan, Shaosong Ye, Chunli Gong, Yu Huang, Yufeng Xiao and 4 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Biomimetic materials for medical applications.Chinese medical journal · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Advances in nanomedicine and delivery systems for gastric cancer research.Frontiers in bioengineering and biotechnology · 2025
    Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Qiang LuoDepartment of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing City, 400037, P. R. China.
Chaoqiang FanDepartment of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing City, 400037, P. R. China.
Wang YingDepartment of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing City, 400037, P. R. China.
Xue PengDepartment of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing City, 400037, P. R. China.
Yiyang HuDepartment of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing City, 400037, P. R. China.
Zhaohui LuanDepartment of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing City, 400037, P. R. China.
Shaosong YeDepartment of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing City, 400037, P. R. China.
Chunli GongDepartment of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing City, 400037, P. R. China.
Yu HuangDepartment of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing City, 400037, P. R. China.
Yufeng XiaoDepartment of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing City, 400037, P. R. China.
Yang ChenDepartment of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing City, 400037, P. R. China.
Malcolm XingDepartment of Mechanical Engineering, Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, R3T 2N2, Canada.
Lei WangCAS Center for Excellence in Nanoscience, CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety National Center for Nanoscience and Technology (NCNST), No. 11 Beiyitiao, Zhongguancun, Beijing, 100190, China.ORCID 0000-0003-1405-9815
Shiming YangDepartment of Gastroenterology, Xinqiao Hospital, Army Medical University, Chongqing City, 400037, P. R. China.
Army Medical University · CNNational Center for Nanoscience and Technology · CNUniversity of Manitoba · CA

Funding

National Natural Science Foundation of China 82003159Science and Technology Innovation Enhancement Project of Army Medical University 2019XQY17
6 · The paper itself

Abstract

With the development of blue laser endoscopy (BLE) technique, it's often used to diagnose early gastric cancer (EGC) by the morphological changes of blood vessels through BLE. However, EGC is still not obvious to identify, resulting in a high rate of missed diagnosis. Molecular imaging can show the changes in early tumors at molecular level, which provides a possibility for diagnosing EGC. Therefore, developing a probe that visually monitors blood vessels of EGC under BLE is particularly necessary. Herein, a bis-pyrene (BP) based nanoprobe (BP-FFVLK-(PEG)-RGD, M

Indexed as

Stomach NeoplasmsAnimalsEndoscopyHumansMiceMolecular ImagingPyrenesRabbitsPyrenesangiogenesisblue laser endoscopyearly gastric cancermolecular imaging

Identifiers

PMID36437107
PMCPMC9896057
OpenAlexW4310276883

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.