Evidence map›Paper›PMID 36436837›Full record

ArticleJournal of child psychology and psychiatry, and allied disciplines2023

Explaining the influence of non-shared environment (NSE) on symptoms of behaviour problems from preschool to adulthood: mind the missing NSE gap.

Agnieszka Gidziela, Margherita Malanchini, Kaili Rimfeld, Andrew McMillan, Angelica Ronald, Essi Viding, Alison Pike, Kathryn Asbury, Thalia C Eley, Sophie von Stumm and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of child psychology and psychiatry, and allied disciplines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Parent-Child Relationships and Locus of Control in Two-Child Families.Psychology in Russia : state of the art · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Agnieszka GidzielaSchool of Biological and Chemical Sciences, Queen Mary University of London, London, UK.ORCID 0000-0002-3400-4638
Margherita MalanchiniSchool of Biological and Chemical Sciences, Queen Mary University of London, London, UK.ORCID 0000-0002-7257-6119
Kaili RimfeldSocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0001-5139-065X
Andrew McMillanSocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Angelica RonaldDepartment of Psychological Sciences, Birkbeck University of London, London, UK.ORCID 0000-0002-9576-2176
Essi VidingDivision of Psychology and Language Sciences, University College London, London, UK.ORCID 0000-0001-8468-8874
Alison PikeSchool of Psychology, University of Sussex, Brighton, UK.
Kathryn AsburyDepartment of Education, University of York, York, UK.
Thalia C EleySocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0001-6458-0700
Sophie von StummDepartment of Education, University of York, York, UK.ORCID 0000-0002-0447-5471
Robert PlominSocial, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.ORCID 0000-0002-0756-3629
King's College London · GBQueen Mary University of London · GBUniversity of York · GBBirkbeck, University of London · GBUniversity College London · GBUniversity of Sussex · GB

Funding

Colorado Adoption/Twin Study of Lifespan behavioral development & cognitive aging (CATSLife2)R01AG046938 · NIA · UNIVERSITY OF COLORADO · PI REYNOLDS, CHANDRA A, WADSWORTH, SALLY J · 2015 to 2024
$18.5M
Medical Research Council G0901245Medical Research Council MR/M021475/1Medical Research Council MR/V012878/1NIA NIH HHS R01 AG046938Wellcome TrustWellcome Trust 213514/Z/18/Z
6 · The paper itself

Abstract

backgroundIndividual differences in symptoms of behaviour problems in childhood and adolescence are not primarily due to nature or nurture - another substantial source of variance is non-shared environment (NSE). However, few specific environmental factors have been found to account for these NSE estimates. This creates a 'missing NSE' gap analogous to the 'missing heritability' gap, which refers to the shortfall in identifying DNA differences responsible for heritability. We assessed the extent to which variance in behaviour problem symptoms during the first two decades of life can be accounted for by measured NSE effects after controlling for genetics and shared environment.

methodsThe sample included 4,039 pairs of twins in the Twins Early Development Study whose environments and symptoms of behaviour problems were assessed in preschool, childhood, adolescence and early adulthood via parent, teacher and self-reports. Twin-specific environments were assessed via parent-reports, including early life adversity, parental feelings, parental discipline and classroom environment. Multivariate longitudinal twin model-fitting was employed to estimate the variance in behaviour problem symptoms at each age that could be predicted by environmental measures at the previous age.

resultsOn average across childhood, adolescence and adulthood, parent-rated NSE composite measures accounted for 3.4% of the reliable NSE variance (1.0% of the total variance) in parent-rated, symptoms of behaviour problems, 0.5% (0.1%) in teacher-rated symptoms and 0.9% (0.5%) in self-rated symptoms after controlling for genetics, shared environment and error of measurement. Cumulatively across development, our parent-rated NSE measures in preschool, childhood and adolescence predicted 4.7% of the NSE variance (2.0% of the total variance) in parent-rated and 0.3% (0.2%) in self-rated behaviour problem symptoms in adulthood.

conclusionsThe missing NSE gap between variance explained by measured environments and total NSE variance is large. Home and classroom environments are more likely to influence behaviour problem symptoms via genetics than via NSE.

Indexed as

Problem BehaviorTwinsAdolescentChild, PreschoolDiseases in TwinsHumansParentsSchoolsBehaviour problem symptomsnon-shared environmenttwin study

Identifiers

PMID36436837
PMCPMC10953036
OpenAlexW4310278099

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.