Evidence map›Paper›PMID 36436793›Full record

ArticleValue in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research2023

Disability-Adjusted Life-Years for Drug Overdose Crisis and COVID-19 Are Comparable During the Two Years of Pandemic in the United States.

Qiushi Chen, Paul M Griffin, Sarah S Kawasaki

Open access · bronzeAbstract read
In one paragraph

Article in Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Qiushi ChenThe Harold and Inge Marcus Department of Industrial and Manufacturing Engineering, The Pennsylvania State University, University Park, PA, USA; Institute for Technology Assessment, Massachusetts General Hospital, Boston, MA, USA. Electronic address: q.chen@psu.edu.
Paul M GriffinThe Harold and Inge Marcus Department of Industrial and Manufacturing Engineering, The Pennsylvania State University, University Park, PA, USA; Consortium for Substance Use and Addiction, Social Science Research Institute, The Pennsylvania State University, University Park, PA, USA.
Sarah S KawasakiPsychiatry and Medicine, Penn State College of Medicine, Hershey, PA, USA; Psychiatry and Internal Medicine, Penn State Health, Hershey, PA, USA.
Massachusetts General Hospital · USPenn State Milton S. Hershey Medical Center · USPennsylvania State University · US

Funding

Comprehensive CBT via reSET for a Hub and Spoke MAT System of CareR33AT010118 · NCCIH · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI CAMPBELL, AIMEE N, HOLDEN, DENISE MICHELLE · 2019 to 2020
$1.4M
6 · The paper itself

Abstract

objectivesThe drug overdose crisis with shifting patterns from primarily opioid to polysubstance uses and COVID-19 infections are 2 concurrent public health crises in the United States, affecting the population of sizes in different magnitudes (approximately < 10 million for substance use disorder [SUD] and drug overdoses vs 80 million for COVID-19 within 2 years of the pandemic). Our objective is to compare the relative scale of disease burden for the 2 crises within a common framework, which could help inform policy makers with resource allocation and prioritization strategies.

methodsWe calculated disability-adjusted life-years (DALYs) for SUD (including opioids and stimulants) and COVID-19 infections, respectively. We collected estimates for SUD prevalence, overdose deaths, COVID-19 cases and deaths, disability weights, and life expectancy from multiple publicly available sources. We then compared age distributions of estimated DALYs.

resultsWe estimated a total burden of 13.83 million DALYs for SUD and drug overdoses and 15.03 million DALYs for COVID-19 in 2 years since March 2020. COVID-19 burden was dominated by the fatal burden (> 95% of total DALYs), whereas SUD burden was attributed to both fatal (53%) and nonfatal burdens (47%). The highest disease burden was among individuals aged 30 to 39 years for SUD (27%) and 50 to 64 years for COVID-19 (31%).

conclusionsDespite the smaller size of the affected population, SUD and drug overdoses resulted in comparable disease burden with the COVID-19 pandemic. Additional resources supporting evidence-based interventions in prevention and treatment may be warranted to ameliorate SUD and drug overdoses during both the pandemic and postpandemic recovery.

Indexed as

COVID-19Drug OverdoseDisability-Adjusted Life YearsHumansPandemicsQuality-Adjusted Life YearsUnited StatesCOVID-19disease burdendrug overdosepopulation healthsubstance use disorder

Identifiers

PMID36436793
PMCPMC9691271
OpenAlexW4310067563

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.