Evidence map›Paper›PMID 36436782›Full record

ArticleTransplantation and cellular therapy2023

Short-Term Storage of Mobilized Peripheral Blood Stem Cells in a Closed System Changes the Microenvironment and May Affect the Quantity of CD34

Amro Elshoury, Orla Maguire, Alexis Conway, Joseph Tario, Kah Teong Soh, Maureen Ross, Theresa Hahn, Joanne Becker, Paul Wallace, Philip L McCarthy and 2 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Transplantation and cellular therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Amro ElshouryWestern New York BloodCare (formerly Hemophilia Center of WNY) and Division of Hematology and Oncology, Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York.
Orla MaguireFlow and Image Cytometry Shared Resource, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Alexis ConwayFlow and Image Cytometry Shared Resource, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Joseph TarioFlow and Image Cytometry Shared Resource, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Kah Teong SohFlow and Image Cytometry Shared Resource, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Maureen RossTransplant & Cellular Therapy Program, Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Theresa HahnDepartment of Cancer Prevention & Control, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Joanne BeckerBlood Bank & Therapeutic Apheresis Unit, Division of Laboratory Medicine, Department of Pathology, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Paul WallaceFlow and Image Cytometry Shared Resource, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Philip L McCarthyTransplant & Cellular Therapy Program, Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
Hans MindermanFlow and Image Cytometry Shared Resource, Roswell Park Comprehensive Cancer Center, Buffalo, New York.
George L ChenTransplant & Cellular Therapy Program, Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, New York. Electronic address: George.chen@roswellpark.org.
Roswell Park Comprehensive Cancer Center · USHemophilia Center of Western Pennsylvania · US

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI Dean G. Tang · 1985 to 2026
$116.6M
Associate-Director Flow and Image Cytometry Roswell Park ComprehensiveCancer CenterR50CA211108 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI HANS MINDERMAN · 2016 to 2026
$3.0M
NCI NIH HHS P30 CA016056NCI NIH HHS R50 CA211108
6 · The paper itself

Abstract

Hypoxic conditions preserve the multipotency and self-renewing capacity of murine bone marrow and human cord blood stem cells. Blood samples stored in sealed blood gas tubes become hypoxic as leukocytes metabolize and consume oxygen. Taken together, these observations suggest that peripheral blood stem cell (PBSC) samples stored under airtight conditions become hypoxic, and that the stem cells contained may undergo qualitative or quantitative changes. This study aimed to determine the effect of storage for 8 hours in a sealed system on PBSC samples. Granulocyte colony-stimulating factor-mobilized PBSC samples were collected prospectively from 9 patients with myeloma or amyloidosis prior to apheresis, followed by measurement of CO

Indexed as

Peripheral Blood Stem CellsAnimalsAntigens, CD34Carbon DioxideCell Adhesion MoleculesHumansLactatesLeukocyte Common AntigensMiceThy-1 AntigensAntigens, CD34Carbon DioxideCell Adhesion MoleculesLactatesLeukocyte Common AntigensThy-1 AntigensGraft collectionGraft processingHematopoiesisHypoxia

Identifiers

PMID36436782
PMCPMC10966894
OpenAlexW4310063360

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.