Evidence map›Paper›PMID 36436190›Full record

ArticleJournal of endocrinological investigation2023

Hyponatremia-related liver steatofibrosis and impaired spermatogenesis: evidence from a mouse model of the syndrome of inappropriate antidiuresis.

G Marroncini, C Anceschi, L Naldi, B Fibbi, M Brogi, L Lanzilao, A Fanelli, M Maggi, A Peri

Open access · hybridAbstract read
In one paragraph

Article in Journal of endocrinological investigation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

G Marroncini *Pituitary Diseases and Sodium Alterations Unit, AOU Careggi, 50139, Florence, Italy.
C Anceschi *Pituitary Diseases and Sodium Alterations Unit, AOU Careggi, 50139, Florence, Italy.
L Naldi *Pituitary Diseases and Sodium Alterations Unit, AOU Careggi, 50139, Florence, Italy.
B FibbiPituitary Diseases and Sodium Alterations Unit, AOU Careggi, 50139, Florence, Italy.
M BrogiCentral Laboratory, Careggi University Hospital, 50139, Florence, Italy.
L LanzilaoCentral Laboratory, Careggi University Hospital, 50139, Florence, Italy.
A FanelliCentral Laboratory, Careggi University Hospital, 50139, Florence, Italy.
M MaggiDepartment of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, AOU Careggi, Viale Pieraccini, 6, 50139, Florence, Italy.
A PeriPituitary Diseases and Sodium Alterations Unit, AOU Careggi, 50139, Florence, Italy. alessandro.peri@unifi.it.ORCID http://orcid.org/0000-0001-6417-434X
Azienda Ospedaliero-Universitaria Careggi · ITUniversity of Florence · IT

Funding

Ministero dell'Università e della Ricerca PRIN 2017R5ZE2C
6 · The paper itself

Abstract

purposeHyponatremia is the most frequent electrolytic disorder in clinical practice. In addition to neurological symptoms, hyponatremia, even when mild/moderate and chronic, has been related to other manifestations, such as bone demineralization and increased risk of fractures. To better elucidate tissue alterations associated with reduced serum sodium concentration [Na METHODS AND

resultsHyponatremia was induced in Foxn1

conclusionOverall, these findings shed new light on the possible consequences of chronic hyponatremia and prompt a more thorough evaluation of hyponatremic patients.

Indexed as

HyponatremiaInappropriate ADH SyndromeAnimalsDeamino Arginine VasopressinLiverMaleMiceSodiumSpermatogenesisVasopressinsDeamino Arginine VasopressinSodiumVasopressinsHyponatremiaLiver steatosisOxidative stressSIADSpermatogenesis

Identifiers

PMID36436190
PMCPMC10105679
OpenAlexW4310276193

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.