Evidence map›Paper›PMID 36436169›Full record

ArticleInternational ophthalmology2023

Brachytherapy as a curative option for ocular surface squamous neoplasia.

Ahmad Rahal, Daniel Meller, Anke Manthey, Nikolaos Bechrakis, Maja Guberina, Martin Stuschke, Henrike Westekemper

Abstract read
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In one paragraph

Article in International ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Innovations in brachytherapy.Taiwan journal of ophthalmology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Ahmad RahalDepartment of Ophthalmology, University Duisburg Essen, Hufelandstrasse 55, 45147, Essen, Germany. ahmdrhl@gmail.com.
Daniel MellerDepartment of Ophthalmology, University Jena, Jena, Germany.
Anke MantheyDepartment of Ophthalmology, University Duisburg Essen, Hufelandstrasse 55, 45147, Essen, Germany.
Nikolaos BechrakisDepartment of Ophthalmology, University Duisburg Essen, Hufelandstrasse 55, 45147, Essen, Germany.
Maja GuberinaDepartment of Radiotherapy, University Duisburg Essen, Essen, Germany.
Martin StuschkeDepartment of Radiotherapy, University Duisburg Essen, Essen, Germany.
Henrike WestekemperDepartment of Ophthalmology, University Duisburg Essen, Hufelandstrasse 55, 45147, Essen, Germany.
University of Duisburg-Essen · DEJena University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOcular surface squamous neoplasia (OSSN) has a high recurrence rate if only treated with surgical excision, especially in cases with positive excision margins. To reduce recurrence, we used brachytherapy after surgical excision for limbal and bulbar lesions in addition to chemotherapy/immunotherapy, cryotherapy, or external beam radiotherapy as adjunctive or primary therapies.

methodsNine eyes with isolated OSSN lesions were included in the study. Adjunctive brachytherapy with Ruthenium

resultsThe average age of patients at the time of presentation was 66 ± 12 years. Follow-up time was 52.8 ± 44.6 months. The maximal tumour base varied between 3 and 28 mm. SCC was confirmed by histology in all cases. No recurrences were recorded during the follow-up, and organ salvage and eye function preservation were achieved. Radiotherapy-induced complications included secondary glaucoma (n = 1) and scleral melting (n = 1). Other complications, such as radiogenic retinopathy, were not observed.

conclusionBrachytherapy with Ruthenium

Indexed as

BrachytherapyCarcinoma, Squamous CellConjunctival NeoplasmsEye NeoplasmsRutheniumAgedHumansMiddle AgedOphthalmologic Surgical ProceduresRetrospective StudiesRutheniumBrachytherapyIntraocular OSSNOSSNRuthenium

Identifiers

PMID36436169
OpenAlexW4310276508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.