Evidence map›Paper›PMID 36435948›Full record

ArticleNature communications2022

Orthogonal glycolytic pathway enables directed evolution of noncanonical cofactor oxidase.

Edward King, Sarah Maxel, Yulai Zhang, Karissa C Kenney, Youtian Cui, Emma Luu, Justin B Siegel, Gregory A Weiss, Ray Luo, Han Li

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  8. EngineeringACS catalysis · 2024
    Article
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Edward King *Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, 92697, USA.
Sarah Maxel *Department Chemical and Biomolecular Engineering University of California Irvine, Irvine, CA, 92697, USA.
Yulai Zhang *Department Chemical and Biomolecular Engineering University of California Irvine, Irvine, CA, 92697, USA.
Karissa C KenneyDepartment of Chemistry, University of California Irvine, Irvine, CA, 92697, USA.
Youtian CuiGenome Center, University of California Davis, Davis, CA, 95616, USA.
Emma LuuGenome Center, University of California Davis, Davis, CA, 95616, USA.ORCID 0000-0002-0388-9330
Justin B SiegelGenome Center, University of California Davis, Davis, CA, 95616, USA.
Gregory A WeissDepartment of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, 92697, USA.ORCID 0000-0003-0296-9846
Ray LuoDepartment of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA, 92697, USA.
Han LiDepartment Chemical and Biomolecular Engineering University of California Irvine, Irvine, CA, 92697, USA. han.li@uci.edu.ORCID 0000-0002-6113-6433
University of California, Irvine · USUniversity of California, Davis · US

Funding

Workshop on Environmental Technology Transfer and EntrepreneurshipP42ES004699 · NIEHS · UNIVERSITY OF CALIFORNIA DAVIS · PI YOUNG, THOMAS MICHAEL · 1987 to 2021
$50.1M
Enzymatic formation of the hydrocarbon skeletons underlying diterpenoid diversityR01GM076324 · NIGMS · IOWA STATE UNIVERSITY · PI PETERS, REUBEN JOHN · 2006 to 2019
$3.4M
Multi-scaled Modeling of Electrostatic and Polarization Effects in BiomoleculesR35GM130367 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI RAY LUO · 2019 to 2026
$3.0M
Engineering an unnatural redox cofactor (uRedox) system for efficient biosynthesis of medicinesDP2GM137427 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI LI, HAN · 2019 to 2022
$2.4M
NIEHS NIH HHS P42 ES004699NIGMS NIH HHS DP2 GM137427NIGMS NIH HHS R01 GM076324NIGMS NIH HHS R35 GM130367
6 · The paper itself

Abstract

Noncanonical cofactor biomimetics (NCBs) such as nicotinamide mononucleotide (NMN

Indexed as

Nicotinamide MononucleotideOxidoreductasesEscherichia coliModels, MolecularMolecular ConformationNicotinamide MononucleotideOxidoreductases

Identifiers

PMID36435948
PMCPMC9701214
OpenAlexW4310009671

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.