Evidence map›Paper›PMID 36435932›Full record

ArticleBotanical studies2022

First report of chemical composition and cytotoxicity evaluation of Foraminispora rugosa basidiomata from Brazil.

V O Garcia, M Fronza, R Von Borowski, G Alves-Silva, A R Zimmer, T Ruaro, S C B Gnoatto, A Dallegrave, R M B Silveira

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Botanical studies, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

V O GarciaInstitute of Biosciences, Federal University of Rio Grande do Sul, Av. Bento Gonçalves 9500, Porto Alegre, Rio Grande do Sul, 91501-970, Brazil. voggarcia@yahoo.com.br.ORCID http://orcid.org/0000-0002-9892-0934
M FronzaUniversity of Vila Velha, Avenida Comissário José Dantas de Melo, 21 - Boa Vista II, Espírito Santo, 29102-920, Brazil.ORCID http://orcid.org/0000-0002-7316-8598
R Von BorowskiFaculty of Pharmaceutical Sciences, Federal University of Rio Grande do Sul, Av. Ipiranga 2752, Porto Alegre, Rio Grande do Sul, 90610-000, Brazil.ORCID http://orcid.org/0000-0003-1764-944X
G Alves-SilvaInstitute of Biosciences, Federal University of Rio Grande do Sul, Av. Bento Gonçalves 9500, Porto Alegre, Rio Grande do Sul, 91501-970, Brazil.ORCID http://orcid.org/0000-0002-8142-6665
A R ZimmerFaculty of Pharmaceutical Sciences, Federal University of Rio Grande do Sul, Av. Ipiranga 2752, Porto Alegre, Rio Grande do Sul, 90610-000, Brazil.ORCID http://orcid.org/0000-0002-8309-7068
T RuaroFaculty of Pharmaceutical Sciences, Federal University of Rio Grande do Sul, Av. Ipiranga 2752, Porto Alegre, Rio Grande do Sul, 90610-000, Brazil.ORCID http://orcid.org/0000-0001-9641-1258
S C B GnoattoFaculty of Pharmaceutical Sciences, Federal University of Rio Grande do Sul, Av. Ipiranga 2752, Porto Alegre, Rio Grande do Sul, 90610-000, Brazil.ORCID http://orcid.org/0000-0002-8806-3182
A DallegraveInstitute of Chemistry, Federal University of Rio Grande do Sul, Av. Bento Gonçalves 9500, Porto Alegre, Rio Grande do Sul, 91501-970, Brazil.ORCID http://orcid.org/0000-0003-4868-2250
R M B SilveiraInstitute of Biosciences, Federal University of Rio Grande do Sul, Av. Bento Gonçalves 9500, Porto Alegre, Rio Grande do Sul, 91501-970, Brazil.ORCID http://orcid.org/0000-0003-1578-5034

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

backgroundForaminispora rugosa is a species reported from Brazil, Venezuela, French Guiana, Costa Rica and Cuba. It is a basidiomycete in the Ganodermataceae family. In this study, both chemical composition and cytotoxicity of the ethanolic extract of F. rugosa were investigated for the first time.

resultsPhylogenetic analysis confirmed the identification of the specimens, and the results of cytotoxicity assays showed that at concentrations of 7.8-500.0 µg/mL the ethanolic extract displayed weak cytotoxicity against the tested cell lines. Five oxylipins were identified by ultra high performance liquid chromatography coupled with quadrupole time-of-flight and mass spectrometry (UHPLC-QTOF-MS).

conclusionsThis study provides new insights into the current knowledge of bioactive compounds produced by macrofungi, and provides data for future biological assays with relative selectivity and safety.

Indexed as

CytotoxicityForaminispora rugosaGanodermataceaeOxylipinsTandem mass spectraTerpenoids

Identifiers

PMID36435932
PMCPMC9701286

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.