ArticleEuropean radiology2023
3D CRANI, a novel MR neurography sequence, can reliable visualise the extraforaminal cranial and occipital nerves.
Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 17 citations in OpenAlex.
- Morphometric and signal intensity benchmarks of 3D CRANI MR neurography sequence for extraforaminal cranial and occipital nerves visualization: a pilot study.Surgical and radiologic anatomy : SRA · 2025Article
- 3D MR Neurography of Craniocervical Nerves: Comparing Double-Echo Steady-State and Postcontrast STIR with Deep Learning-Based Reconstruction at 1.5T.AJNR. American journal of neuroradiology · 2025Article
- Compartmentalization of High Infratemporal Fossa in Oral Cavity Squamous Cell Carcinomas and Its Impact on Clinical Outcome.Current oncology (Toronto, Ont.) · 2025Observational
- Fusion of contrast-enhanced magnetic resonance neurography and T1-weighted imaging improves simultaneous nerve-tumor visualization in head and neck lesions.Frontiers in oncology · 2025Article
- Contrast-enhanced magnetic resonance neurography for diagnosing brachial plexopathy: improved visualization and additional imaging features.Scientific reports · 2024Article
- Visualization of the Facial Nerve with Ultra-high-Frequency Ultrasound.Plastic and reconstructive surgery. Global open · 2023Article
- The ptotic tongue-imaging appearance and pathology localization along the course of the hypoglossal nerve.Neuroradiology · 2023Review
- Visualization of clinically silent, odontogenic maxillary sinus mucositis originating from periapical inflammation using MRI: a feasibility study.Clinical oral investigations · 2023Article
- MR-orthopantomography in operative dentistry and oral and maxillofacial surgery: a proof of concept study.Scientific reports · 2023Article
- Magnetic resonance imaging for diagnosis of suspected neurogenic thoracic outlet syndrome-a systematic scoping review.Frontiers in physiology · 2023Article
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWe aim to validate 3D CRANI, a novel high-field STIR TSE, MR neurography sequence in the visualisation of the extraforaminal cranial and occipital nerve branches on a 3-T system. Furthermore, we wish to evaluate the role of gadolinium administration and calculate nerve benchmark values for future reference.
methodsEleven consecutive patients underwent MR imaging including the 3D CRANI sequence before and immediately after intravenous gadolinium administration. Two observers rated suppression quality and nerve visualisation using Likert scales before and after contrast administration. Extraforaminal cranial and occipital nerves were assessed. Nerve calibers and signal intensities were measured at predefined anatomical landmarks, and apparent signal intensity ratios were calculated.
resultsThe assessed segments of the cranial and occipital nerves could be identified in most cases. The overall intrarater agreement was 79.2% and interrater agreement was 82.7% (intrarater κ = .561, p < .0001; interrater κ = .642, p < .0001). After contrast administration, this significantly improved to an intrarater agreement of 92.7% and interrater agreement of 93.6% (intrarater κ = .688, p < .0001; interrater κ = .727, p < .0001). Contrast administration improved suppression quality and significant changes in nerve caliber and signal intensity measurements. Nerve diameter and signal intensity benchmarking values were obtained.
conclusion3D CRANI is reliable for the visualization of the extraforaminal cranial and occipital nerves. Intravenous gadolinium significantly improves MR neurography when applying this sequence. Benchmarking data are published to allow future assessment of the 3D CRANI sequence in patients with pathology of the extraforaminal cranial and occipital nerves. KEY POINTS: • MR neurography using the 3D CRANI sequence is a reliable method to evaluate the extraforaminal cranial and occipital nerves. • Gadolinium contrast administration significantly improves suppression quality and nerve visualisation. • Benchmarking values including apparent signal intensity ratios and nerve calibers depend on contrast administration and might play an important role in future studies evaluating extraforaminal cranial and occipital neuropathies.
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