Evidence map›Paper›PMID 36435871›Full record

ArticleNature communications2022

Greater genetic diversity is needed in human pluripotent stem cell models.

Sulagna Ghosh, Ralda Nehme, Lindy E Barrett

Abstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

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  14. Modelling human brain development and disease with organoids.Nature reviews. Molecular cell biology · 2025
    Review
  15. Somatic and Stem Cell Bank to study the contribution of African ancestry to dementia: African iPSC Initiative.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sulagna GhoshStanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. sulagna.ghosh@gmail.com.ORCID 0000-0003-1833-7296
Ralda NehmeStanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. rnehme@broadinstitute.org.ORCID 0000-0001-7215-3311
Lindy E BarrettStanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. lbarrett@broadinstitute.org.ORCID 0000-0002-3229-4774

Funding

Genetic neuroscience: How human genes and alleles shape neuronal phenotypesU01MH115727 · NIMH · BROAD INSTITUTE, INC. · PI ARLOTTA, PAOLA, BABADI, MEHRTASH · 2017 to 2021
$20.8M
Dissecting the role of FMRP in RNA processing using hPSC modelsR01HD101534 · NICHD · BROAD INSTITUTE, INC. · PI BARRETT, LINDY ELISE · 2020 to 2022
$4.1M
NICHD NIH HHS R01 HD101534NIMH NIH HHS U01 MH115727
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Induced Pluripotent Stem CellsPluripotent Stem CellsGenetic VariationHumans

Identifiers

PMID36435871
PMCPMC9701202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.