Evidence map›Paper›PMID 36435846›Full record

ReviewBiomaterials research2022

Recent biomedical advancements in graphene oxide- and reduced graphene oxide-based nanocomposite nanocarriers.

Naline Bellier, Phornsawat Baipaywad, Naeun Ryu, Jae Young Lee, Hansoo Park

Open access · goldAbstract readReview
In one paragraph

Review in Biomaterials research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
10.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 145 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Naline Bellier *School of Integrative Engineering, Chung-Ang University, Seoul, 06974, Republic of Korea.
Phornsawat Baipaywad *School of Integrative Engineering, Chung-Ang University, Seoul, 06974, Republic of Korea.
Naeun RyuSchool of Integrative Engineering, Chung-Ang University, Seoul, 06974, Republic of Korea.
Jae Young LeeSchool of Materials Science and Engineering, Gwangju Institute of Science and Technology, Gwangju, 61005, Republic of Korea. jaeyounglee@gist.ac.kr.ORCID http://orcid.org/0000-0003-4493-2494
Hansoo ParkSchool of Integrative Engineering, Chung-Ang University, Seoul, 06974, Republic of Korea. heyshoo@cau.ac.kr.
Chung-Ang University · KRChiang Mai University · THGwangju Institute of Science and Technology · KR

Funding

Ministry of Science and ICT (KR) NRF-2021R1A4A3025206
6 · The paper itself

Abstract

Recently, nanocarriers, including micelles, polymers, carbon-based materials, liposomes, and other substances, have been developed for efficient delivery of drugs, nucleotides, and biomolecules. This review focuses on graphene oxide (GO) and reduced graphene oxide (rGO) as active components in nanocarriers, because their chemical structures and easy functionalization can be valuable assets for in vitro and in vivo delivery. Herein, we describe the preparation, structure, and functionalization of GO and rGO. Additionally, their important properties to function as nanocarriers are presented, including their molecular interactions with various compounds, near-infrared light adsorption, and biocompatibility. Subsequently, their mechanisms and the most appealing examples of their delivery applications are summarized. Overall, GO- and rGO-based nanocomposites show great promise as multipurpose nanocarriers owing to their various potential applications in drug and gene delivery, phototherapy, bioimaging, biosensing, tissue engineering, and as antibacterial agents.

Indexed as

DeliveryDrug loadingFunctionalizationNanomedicineTherapeutic biomolecules

Identifiers

PMID36435846
PMCPMC9701399
OpenAlexW4309988245

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.