ArticleBMC pregnancy and childbirth2022
The prevalence and associated factors of prenatal depression and anxiety in twin pregnancy: a cross-sectional study in Chongqing, China.
Article in BMC pregnancy and childbirth, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Pregnancy with multiple high-risk factors: a systematic review and meta-analysis.Journal of global health · 2025Pooled it
- Prevalence of Perinatal Anxiety and Related Disorders in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis.JAMA network open · 2023Pooled it
- Exploring the lived experiences of pregnant women regarding the challenges and needs of higher-order multiple pregnancies in Western Iran: a phenomenological descriptive study.BMC public health · 2025Article
- Prenatal Diagnosis of Acrania in One Twin of a Dichorionic Diamniotic Pregnancy: A Case Report on Management and Perinatal Outcome.Reports (MDPI) · 2025Article
- Effect of mindfulness group therapy on maternal psychological distress and perinatal outcomes in twin pregnancy: a randomized controlled trial.Frontiers in psychiatry · 2025Article
- Pregnancy stress in women at high risk of preeclampsia with their anxiety, depression, self-management capacity: a cross-sectional study.Frontiers in psychology · 2025Article
- Association between prenatal maternal sleep quality, neonatal uncinate fasciculus white matter, and infant negative emotionality.EBioMedicine · 2024Article
- Prevalence and factors associated with antenatal depressive symptoms across trimesters: a study of 110,584 pregnant women covered by a mobile app-based screening programme in Shenzhen, China.BMC pregnancy and childbirth · 2024Article
- Article
- Exploring the lived experiences of women with multiple gestations in Iran: a phenomenological study.BMC pregnancy and childbirth · 2024Article
- Impact of closed-off management due to COVID-19 rebound on maternal depression during pregnancy.BMC pregnancy and childbirth · 2024Article
- Comorbid Anxiety and Depression among Pregnant and Postpartum Women: A Longitudinal Population-Based Study.Depression and anxiety · 2024Article
- Exploring the sports participation, muscle-strengthening exercise and active commuting with comorbidity of depression and anxiety among Chinese children and adolescents: a cross-sectional study.Frontiers in psychology · 2024Article
- Development and validation of a prediction model on spontaneous preterm birth in twin pregnancy: a retrospective cohort study.Reproductive health · 2023Article
- Article
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundPregnant women expecting twins are more likely to experience stress, which can lead to anxiety and depression. Our aim was to investigate the prevalence of prenatal anxiety and depressive symptoms in women with twin pregnancies and the associated factors.
methodsIn a cross-sectional survey, 210 women with twin pregnancies who satisfied the inclusion and exclusion criteria in two tertiary centers in Southwestern China were asked to complete a basic information form, the Self-Rating Anxiety Scale (SAS) and the Self-Rating Depression Scale (SDS). To compare statistics with normal distribution in distinct characteristic groups, a paired t-test, and one-way ANOVA were utilized. Binary logistic step regression was used to analyze the associated factors of antenatal anxiety and depressive symptoms.
resultsThe 210 women with twin pregnancies (age = 30.8 ± 4.2 years) were between 7 and 37 gestational weeks (29.2 ± 1.2 weeks), were typically well-educated (72.4% had a post-high-school degree), and reasonably affluent (88.1% were above the low-income cutoff). Among them, 34.8% had symptoms associated with clinical levels of anxiety, and 37.1% had symptoms indicating possible depression. The prevalence of co-morbid anxiety and depressive symptoms was 24.3%. Binary stepwise logistic regression analysis showed that previous health status and sleep disturbance during pregnancy were the associated factors of anxiety symptoms in women with twin pregnancies (P < 0.05), whereas age, previous health status, negative life events, and physical activity during pregnancy were the associated factors of depressive symptoms in women with twin pregnancies (P < 0.05).
conclusionAbout one-third of women with twin pregnancies had symptoms of anxiety or depression; these were most strongly predicted by some modifiable factors, suggesting that early preventive mind-body interventions may be a promising strategy to protect against mental health issues for women with twin pregnancies.
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