ArticleGynecologic oncology2023
Racial and ethnic differences in type II endometrial cancer mortality outcomes: The contribution of sociodemographic, clinicopathologic, and treatment factors.
Article in Gynecologic oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 43 citations in OpenAlex.
- A Retrospective Cohort Study of Uterine Cancer Epidemiological Analysis and Age-Based Disparities in Saudi Arabian Population across 32 Years.Saudi medical journal · 2026Article
- A Bayesian mixture model approach to examining neighbourhood social determinants of health in endometrial cancer care in Massachusetts.Journal of the Royal Statistical Society. Series A, (Statistics in Society) · 2026Article
- Racial and Ethnic Disparities in Cancer Mortality and Mediating Effects of Sociodemographic, Clinicopathologic, and Treatment Factors.Journal of racial and ethnic health disparities · 2025Article
- Gynecologic Oncology Patients have Urobiomes that are Similar to Women Without Gynecologic Cancer.International urogynecology journal · 2025Article
- Risk factors for delayed diagnosis of endometrial cancer among black individuals: Results from the GUIDE-EC study.Gynecologic oncology reports · 2025Article
- A Comparison of Neighborhood Socioeconomic Deprivation Measures and the Association with Survival among Black and White Women with Endometrial Cancer.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Article
- Establishment and validation of a prognostic nomogram for overall survival in type II endometrial carcinoma patients.Scientific reports · 2025Article
- Differential Colorectal Cancer Mortality Across Racial and Ethnic Groups: Impact of Socioeconomic Status, Clinicopathology, and Treatment-Related Factors.Cancer medicine · 2025Article
- Beyond Bleeding: An Analysis of Presenting Symptoms Among Black Patients with Endometrial Cancer.Health equity · 2025Article
- AI-powered advances in type II endometrial cancer: global trends and African contexts.Frontiers in oncology · 2025Review
- Strategies, Challenges, and Prospects of Nanoparticles in Gynecological Malignancies.ACS omega · 2024Review
- Article
- Article
- Mitigating disparity?: Treatment patterns, survival, and recurrence rates by race, ethnicity, and hospital site across a large urban health system.Gynecologic oncology reports · 2024Article
- Review
- Race, Prevalence of POLE and POLD1 Alterations, and Survival Among Patients With Endometrial Cancer.JAMA network open · 2024Article
- Comparison of clinical characteristics and prognosis in endometrial carcinoma with different pathological types: a retrospective population-based study.World journal of surgical oncology · 2023Article
- Racial/ethnic and socioeconomic differences in breast cancer surgery performed and delayed treatment: mediating impact on mortality.Breast cancer research and treatment · 2023Article
- Natural products modulate cell apoptosis: a promising way for treating endometrial cancer.Frontiers in pharmacology · 2023Review
- Disparities in Gynecologic Cancers.Cancer journal (Sudbury, Mass.)Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThe burden of type II endometrial cancer (EC) is rising dramatically in the U.S. Although type II EC disproportionately affects Black women, the magnitude of racial/ethnic differences in type II EC mortality outcomes and factors underlying these differences remain understudied. We examined racial/ethnic differences in cancer-specific and overall mortality in women with type II EC and quantified the extent to which mortality differences are mediated by sociodemographic, clinicopathologic, and treatment factors.
methods14,710 women ≥18 years with type II EC from 2007 to 2016 were identified from the Surveillance, Epidemiology, and End Results database. The association between race/ethnicity (non-Hispanic White [NHW], non-Hispanic Black [NHB], Hispanic, and non-Hispanic Asian/Pacific Islander [NHAPI]) and cancer-specific and overall mortality was examined. Mediation analysis was used to identify factors underlying differences in mortality outcomes.
resultsNHB women had a higher risk of cancer-specific mortality than NHW women (hazard ratio [HR]: 1.22, 95% CI: 1.12-1.33), whereas NHAPI (HR: 0.88, 95% CI: 0.78-0.99) and Hispanic women (HR: 0.91, 95% CI: 0.81-1.01) had a lower risk of cancer-specific mortality than NHW women. Differences in clinicopathologic (stage, grade, histologic subtype), sociodemographic (insurance type, geographic region and location, neighborhood socioeconomic status), and treatment factors (treatment type, lymphadenectomy) explained 43.5%, 8.1%, and 7.3% of the difference in cancer-specific mortality between NHB and NHW women, respectively. Similar results were noted for overall mortality.
conclusionsMultidisciplinary and multilevel approaches that integrate and address social and biological factors are needed to reduce the disproportionate burden of type II EC mortality in NHB women.
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