Evidence map›Paper›PMID 36434848›Full record

ReviewJournal of electrocardiology

Continuous ECG monitoring should be the heart of bedside AI-based predictive analytics monitoring for early detection of clinical deterioration.

Oliver J Monfredi, Christopher C Moore, Brynne A Sullivan, Jessica Keim-Malpass, Karen D Fairchild, Tyler J Loftus, Azra Bihorac, Katherine N Krahn, Artur Dubrawski, Douglas E Lake and 2 more

Open access · greenAbstract readReview
In one paragraph

Review in Journal of electrocardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Time-series ECG Imputation Using a Pattern-Based Masking Framework.medRxiv : the preprint server for health sciences · 2026
    Article
  4. Review
  5. A Review of Racial Differences and Disparities in ECG.International journal of environmental research and public health · 2025
    Review
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Oliver J MonfrediCenter for Advanced Medical Analytics, University of Virginia, United States of America; Department of Medicine, University of Virginia, United States of America.
Christopher C MooreCenter for Advanced Medical Analytics, University of Virginia, United States of America; Department of Medicine, University of Virginia, United States of America.
Brynne A SullivanCenter for Advanced Medical Analytics, University of Virginia, United States of America; Department of Pediatrics, University of Virginia, United States of America.
Jessica Keim-MalpassCenter for Advanced Medical Analytics, University of Virginia, United States of America; School of Nursing, University of Virginia, United States of America.
Karen D FairchildCenter for Advanced Medical Analytics, University of Virginia, United States of America; Department of Pediatrics, University of Virginia, United States of America.
Tyler J LoftusDepartment of Surgery, University of Florida, United States of America.
Azra BihoracDepartment of Medicine, University of Florida, United States of America.
Katherine N KrahnCenter for Advanced Medical Analytics, University of Virginia, United States of America; Department of Medicine, University of Virginia, United States of America.
Artur DubrawskiRobotics Institute, Carnegie Mellon University, United States of America.
Douglas E LakeCenter for Advanced Medical Analytics, University of Virginia, United States of America; Department of Medicine, University of Virginia, United States of America.
J Randall MoormanCenter for Advanced Medical Analytics, University of Virginia, United States of America; Department of Medicine, University of Virginia, United States of America. Electronic address: rm3h@virginia.edu.
Gilles ClermontDepartment of Critical Care, University of Pittsburgh, United States of America.
University of Virginia · USUniversity of Florida · USCarnegie Mellon University · USUniversity of Pittsburgh · US

Funding

Bridge2AI: Patient-Focused Collaborative Hospital Repository Uniting Standards (CHoRUS) for Equitable AIOT2OD032701 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI BIHORAC, AZRA, CLERMONT, GILLES · 2022 to 2025
$24.6M
Predictive Informatics Monitoring in the Neonatal Intensive Care UnitR01HD072071 · NICHD · UNIVERSITY OF VIRGINIA · PI KAREN D FAIRCHILD, Brynne Archer Sullivan · 2014 to 2026
$7.6M
Prematurity-Related Ventilatory Control: Leadership Data and Coordination Center (LDCC)U01HL133708 · NHLBI · UNIVERSITY OF VIRGINIA · PI LAKE, DOUGLAS E, MOORMAN, JOSEPH RANDALL · 2016 to 2020
$3.7M
A randomized clinical trial of early empiric anti-Mycobacterium tuberculosis therapy for sepsis in sub-Saharan AfricaU01AI150508 · NIAID · UNIVERSITY OF VIRGINIA · PI HEYSELL, SCOTT K, MOORE, CHRISTOPHER CHARLES · 2020 to 2024
$3.3M
Integrated physiomarker, biomarker and clinical predictive analytics for early warning of sepsis and necrotizing enterocolitis in very low birth weight infants.K23HD097254 · NICHD · UNIVERSITY OF VIRGINIA · PI SULLIVAN, BRYNNE ARCHER · 2019 to 2023
$897k
Aligning Patient Acuity with Intensity of Care after SurgeryK23GM140268 · NIGMS · UNIVERSITY OF FLORIDA · PI LOFTUS, TYLER J · 2020 to 2023
$619k
NHLBI NIH HHS U01 HL133708NIAID NIH HHS U01 AI150508NICHD NIH HHS K23 HD097254NICHD NIH HHS R01 HD072071NIGMS NIH HHS K23 GM140268NIH HHS OT2 OD032701
6 · The paper itself

Abstract

The idea that we can detect subacute potentially catastrophic illness earlier by using statistical models trained on clinical data is now well-established. We review evidence that supports the role of continuous cardiorespiratory monitoring in these predictive analytics monitoring tools. In particular, we review how continuous ECG monitoring reflects the patient and not the clinician, is less likely to be biased, is unaffected by changes in practice patterns, captures signatures of illnesses that are interpretable by clinicians, and is an underappreciated and underutilized source of detailed information for new mathematical methods to reveal.

Indexed as

Clinical DeteriorationElectrocardiographyArtificial IntelligenceHumansModels, StatisticalMonitoring, PhysiologicCardiorespiratory monitoringPredictive monitoring

Identifiers

PMID36434848
PMCPMC10061545
OpenAlexW4308149553

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.